G6PD

G6PD

Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids, via the liver adipose tissue mammary glands and adrenals. Has an important role in erythrocyte functions Levels are used to determine potential haemolytic anaemia. Haemolysis can be set off by certain triggers including pathogens. Via NADPH it plays an essential role in the Glutathione recycling pathway, low levels show a potential propensity to oxidative stress and acts a protective agent for protecting erythrocytes against oxidative stress and removal of hydrogen peroxide.

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