Advanced cardiovascular health profile
Heart disease is the second leading cause of adult deaths in the UK and the number one disease affecting men. Almost 50% of all heart attack patients display traditional early warning markers for cardiovascular disease (CVD).
This is why Functional DX has carefully curated the Cardio Check Panel, a state-of-the-art panel reporting on over 110 markers.
Our comprehensive panel includes: Homocysteine, Apolipoprotein A1, Apolipoprotein B, Lipoprotein (a), LpPla2, Fibrinogen, fatty acids, and glycaemic markers. It also measures a myriad of other biomarkers including vitamins, minerals, antioxidants, and organic acids. Enabling you to identify general health trends, accurately assess the health status of the other body systems, nutrient needs, and underlying clinical patterns crucial for heart and human health.
Our thorough investigative tests will help you with identifying any current underlying issues as well as with the prevention of health deterioration. Making our Cardio Check blood test and reporting the ultimate tool for the modern healthcare practitioner to identify and monitor the health status and trends of your client’s heart health.
Our FDX Cardio Check panel has been created to look further than the norm (traditional blood analysis) to reveal more about your client’s health picture and to identify areas to focus an effective treatment plan. FunctionalDX uses the world’s most advanced blood interpretation technology considers 13 body systems, 7 accessory systems, 7 macronutrient systems, 14 micro-nutrient deficiencies and 40+ clinical dysfunctions.
Apo A is a constituent of HDL and assists in the binding of cholesterol and fats transport from blood vessels and cells preventing plaque formation. It has a role in cognitive function, in the immune system as an agent against pathogens and detoxifies bacterial toxins. Used as a predictor for CVD and inflammation.See full description
Apolipoprotein B is the backbone of LDL, and is part of the delivery system to deliver cholesterol from the liver. A main contributor to atherosclerosis and heart disease. Linked to immune function and is a measure of CVD risk. Levels are linked with obesity, hypothyroidism, insulin resistance and diabetes. Risk factors also include Alzheimer’s, cognitive function, heart disease and possibly cancer.See full description
Used a coronary biomarker. Levels are used to assess risks and trends to coronary artery disease, atherosclerosis, CVD, myocardial infarction, and stroke.See full description
A byproduct of proinsulin production by the pancreas. Proinsulin splits into Insulin and C-Peptide. Unlike Insulin which is cleared in a variable manner c-peptide is cleared at a constant rate making it a more dependable measure of Insulin production. Levels indicate how much Insulin is being produced and indicates blood sugar dysregulation including Type 1 and 2 diabetes.See full description
45% of calcium is inactive and bound to albumin, of the rest 45% is free and active. The calcium test measures total calcium. Calcium an alkali earth metal is essential for muscle contraction, oocyte activations, bone and dental health, blood clotting, nerve impulse transmission, heartbeat regulation and intracellular fluid balance. Levels are used to assess calcium sufficiency, parathyroid function, hydrochloric acid, tissue cell damage, thyroid function, vitamin D sufficiency, Osteoporosis, acid base balance, ovarian function.See full description
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases. Used to assess copper sufficiency, inflammation needs for copper, zinc, anaemia, toxicity, and immune function. Is also used as an Alzheimer’s risk marker, Parkinson’s, Iron status, obesity, and liver damage.See full description
Groups of enzymes that play a large role in energy production and found in tissues that use lots of energy i.e. heart, skeletal muscle and the brain. Levels are used to assess damage from the heart (MI), skeletal muscle damage and breakdown, brain damage, and muscle atrophySee full description
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones progesterone, testosterone and the oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an inﬂuence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead to many common conditions in the endocrine, immune, cardiovascular, hormonal, and nervous systems.See full description
Synthesised from cholesterol, this steroid hormone is produced in the ovaries of premenopausal women, where it acts as a powerful reproductive hormone and is highest during ovulation and lowest during menstruation. As the main hormone of the three naturally produced oestrogens, it is also produced in the testes of men, but in smaller amounts. In both sexes, oestradiol is made in significantly reduced amounts by the brain, fat tissue, and in the walls of the blood vessels.See full description
A measure of the amount of iron stored in the body. The most sensitive test to assess iron deficiency. Levels may indicate haemochromatosis, excess iron intake, inflammation, oxidative stress, liver dysfunction, excessive blood loss or iron deficiency anaemia.See full description
A soluble liver produced protein that is broken down to produce fibrin which is necessary for clot formation. Levels may indicate hypercoagulation, inflammation, trauma, infections, cancer, cardiovascular disease or increased risk of stroke and liver function.See full description
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 2 to 3 weeks. Levels may indicate blood sugar dysregulation.See full description
Similar in structure to insulin, insulin-like growth factor-1 plays a prominent role in the regulation of immunity and inflammation, and an essential role in regulating endocrine growth and development. It works together with the growth hormone (GH) and stimulates the liver to produce IGF-1 which reproduces, and regenerates cells and promotes growth and development. Another important function is to strengthen tissues, thereby improving bone density and building muscle, and promoting healing.See full description
A fasting insulin test identifies the level of insulin after an 8 to 12 hour fast. Insulin is a pancreatic hormone released to manage the process of glucose being transported into the cells for energy production purposes. Levels are associated with Insulin resistance, Diabetes, Metabolic Syndrome, inflammation, Obesity, lipid management and risks of CVD.See full description
Made in the liver comprising of LDL, Apolipoprotein B and apolipoprotein(a). (note not to be confused with Apo A). It is an independent marker and levels are largely dependent on genetic propensity. It is used to assess CVD risk, heart disease and stroke.See full description
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary markerSee full description
A measure of the ratio of fatty acids in the blood. This test and report are a measurement and report on the levels of omega 3, 6, 5, 7 and 9 fatty acids as well as saturated and trans along with ratios and indexes. Levels may indicate deficiencies, needs and excess, assessment for dietary malabsorption, as well as indicating inflammation and cardiovascular disease risk.See full description
See Folate. Red cell folate is considered to be a measure for intracellular sufficiency.See full description
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function, maintenance of strong bones, carbohydrate and protein metabolism, and over 300 enzymatic processes in the body. It is obtained through diet and is absorbed in the small intestine and colon. Levels may indicate deficiency due to malabsorption or gastrointestinal disorders.See full description
An essential micronutrient. As soils become depleted dietary intake has fallen, and the need to assess increases. Essential for thyroid T4 to T3 conversion, protects LDL from oxidation. Levels used to assess immune function, inflammation, heart disease risk and reproduction capacity esp. male fertility, Protective effect against some cancers.See full description
This protein is produced by the liver, controlled by sex hormones, thyroid hormones, insulin, and dietary factors and binds to sex hormones - testosterone, DHT (dihydrotestosterone), and oestrogen (estradiol). It helps transport them in the blood. SHBG levels, which change with age, vary between men and women, and can help control the levels of androgens and oestrogens in the body. It can help to determine testosterone levels in the blood, since around 40-60% of total testosterone is bound to SHBG in men.See full description
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a serum level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.See full description
You will need a main test first
LDH is made up of a number of enzymes that are contained in different body tissues. This test identifies the levels of the different LDH enzymes so tat the site of damage, dysfunction and imbalance can be identified.
Comprehensive Male Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more
Comprehensive Female Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more.
Investigation for identifying autoimmune disease on the TSH receptors usually prevalent in Grave's disease (90%).
An Epstein-Barr virus (EBV) antibodies investigation can indicate a current, recent, or past EBV infection. Including: IgG, IgM and Anti Nuclear Antigen (ANA)
An Helicobacter Pylori Antibodies investigation can indicate recent past or longer term past H. Pylori infection
Anti Mullerian Hormone investigation useful for understanding ovarian reserve and can be used in assessment of PCOS.
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia. and the effects of supplementation in the case of B12, B6 and Folate anaemias.
C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C4 is Important for the body’s immune function and response to inflammation originating from the HLA system
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
Measurement of IgG, IgM, IgE Immunoglobulins in investigations of the immune system
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, Testosterone and DHT. DHT is the most potent hormone amongst the androgens because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5 alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to the tissue in which it is produced. It is a more potent hormone than testosterone (approx. 1% circulated feely as unbound), it has a slow dissociation (approx. 5x less than testosterone) and long half-life (2x affinity to the androgen receptors). During development and adult life in men, it promotes prostate growth, activity of the sebaceous glands, male pattern baldness and the development of characteristics that are typically associated with men (body hair, muscle growth, and a deep voice). In women DHT levels are associated with issues including hirsutism, amenorrhea, and increased acne.
Cancer Markers: CA19-9, CA125, CA15-3
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a red blood cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
Fasting blood draw required in the morning.