Total Thyroid markers
FDX 24
Our Thyroid Check Plus is the next level up from our Thyroid Check (FDX23) test. It includes all of the markers in the Thyroid Check. In order to reveal possible further thyroid imbalances, we have added additional biomarkers that include receptor antibody markers which can help to identify autoimmune responses.
Once Hypothyroidism or Hyperthyroidism is suspected, our objective as clinicians, is to avoid further thyroid degeneration such as Autoimmune Graves’ and Hashimoto’s thyroiditis, some of the most frequent autoimmune disorders.
Our Thyroid Check Plus panel also tests for Epstein-Barr virus (EBV). This is one of the most considered viral infections linked in autoimmune Thyroiditis, as well as thyroglobulin and TSH receptor antibodies.
£289.00
Key Biomarker
The rate of sedimentation of red blood cells in anti-coagulated blood in one hour. Levels may indicate tissue destruction, inflammation, and may indicate in certain cases presence of pathogens.
See full descriptionKey Biomarker
The portion of triiodothyronine (T3) that is not bound and represents approximately 10% of circulating T3 in the blood. T3 is converted from T4 and the majority occurs in the liver and kidneys. The conversion process is dependent on Selenium and bile levels. Levels can be used to assess Hypo and hyper thyroid status, T4 to T4 conversion efficacy, Selenium sufficiency, and Iodine sufficiency.
See full descriptionKey Biomarker
Less than 0.05% of Total Thyroxine (T4) is free or unbound. The hormone is made in the thyroid gland and is the precursor to T3. Production of T4 is dependent on levels of iodine, co factors like B6, Biopterin, Copper, Zinc, Vitamins B2, B3 and A. Considered by mainstream when combined with TSH to be the gold standard for assessing thyroid function., Levels are assessed to identify thyroid status (hypo and hyper), Iodine sufficiency as well as protein status and liver function.
See full descriptionKey Biomarker
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
See full descriptionKey Biomarker
Used to assess thyroid hormone conversion, stress, elevated cortisol.
See full descriptionKey Biomarker
Also known as T3 resin uptake. Measures the number of unbound sites on the thyroid binding proteins. Levels are used to identify thyroid states (hypo and hyper) as well as selenium and iodine sufficiency. Can also be used to identify how much binding globulins are available to bind to thyroid hormones.
See full descriptionKey Biomarker
A marker to determine how much active T4 is available ie how well the thyroid is functioning. Used to determine hypo and hyper thyroid status.
See full descriptionKey Biomarker
Also known as TG Abs. Used to determine if there is a thyroid autoimmune dysfunction ie Hashimoto’s (Hypo) or Graves (hyper) where the thyroglobulin in the thyroid is attacked.
See full descriptionKey Biomarker
Also known as TPO. TPO is a thyroid gland produced enzyme that attaches the Iodine molecule to tyrosine to make T4. Levels are used to determine an autoimmune thyroid condition - Hashimoto’s.
See full descriptionKey Biomarker
Aka TBG Made in the liver. TBG is a protein that binds and carries T4 and T3 in the blood. There are also other proteins that carry thyroid hormones ie Albumin and Transthyretin. Especially useful where T4 and T3 don't have accompanying thyroid symptoms as levels can also be related to oestrogen, corticosteroids, and liver function.
See full descriptionKey Biomarker
Represents the total of free and bound T3 in the blood, represents approximately 90% of T3. A small percentage is made directly in the thyroid gland and rest predominantly made in the liver and kidney by the conversion of T4 to T3. Levels are used to determine T4 conversion syndrome, Euthyroid sick syndrome, Selenium and Iodine sufficiency and Hyperthyroidism.
See full descriptionKey Biomarker
Major thyroid hormone secreted by the thyroid gland and subject to appropriate levels of Biopterin, Vitamins B6, B2, A, B3 and C as well as sufficient Copper and Zinc. Total T4 represents over 99.5% of the total thyroid hormone available. Levels can help determine, thyroid status (hypo or hyper), Iodine sufficiency,
See full descriptionKey Biomarker
Thyroid Stimulating Hormone is secreted from the anterior pituitary gland and levels are based on a negative feedback loop to signal to the thyroid gland whether to release more Thyroxine or stop releasing. Conventionally along with free T4 the combination is considered the gold standard for assessing thyroid status. Levels are also affected by heavy metal burdens including Aluminium.
See full descriptionKey Biomarker
Also known as TRAbs. Measure the number of antibodies produced antagonistically against the thyroid stimulating receptor. These receptors signal the thyroid to produce thyroid hormones and autoimmune conditions cause the receptors to malfunction. Levels are used to determine Graves' disease (hyperthyroid 90%) and also can be indicated in Hashimoto's (hypothyroid 10%).
See full description
Blood Chemistry
A type of white blood cell (granulocyte) that alerts the body to infection by secreting immune substances that influence inflammation and coagulation. In tissues they are referred to as mast cells. These specialised immune cells play an important role in inflammation and prevention of clotting in inflamed tissues. Levels may indicate inflammation, intestinal parasites, infection, endocrine dysfunction or hypothyroidism.
See full descriptionBlood Chemistry
A type of white blood cell (granulocyte) that alerts the body to infection by secreting immune substances that influence inflammation and coagulation. In tissues they are referred to as mast cells. These specialised immune cells play an important role in inflammation and prevention of clotting in inflamed tissues. Levels may indicate inflammation, intestinal parasites, infection, endocrine dysfunction, or hypothyroidism.
See full descriptionBlood Chemistry
A type of white blood cell (granulocyte) that secretes important immune substances that influence the inflammatory response. These specialised immune cells are primarily involved in allergic reactions and in host defense against parasitic infection. Levels may indicate intestinal parasites, food/environmental allergies or sensitivities, chronic stress or atopic conditions.
See full descriptionBlood Chemistry
A type of white blood cell (granulocyte) that secretes important immune substances that influence the inflammatory response. These specialised immune cells are primarily involved in allergic reactions and in host defense against parasitic infection. Levels may indicate intestinal parasites, food/environmental allergies or sensitivities, chronic stress or atopic conditions.
See full descriptionBlood Chemistry
A measure of the percentage of blood volume that consists of red blood cells in a given percentage of centrifuged red blood. Levels may indicate dehydration, malabsorption, asthma, adrenal dysfunction, blood loss, gastric inflammation, thymus hypofunction, liver disease, hypothyroidism, or nutrient deficiencies or anaemia from iron, B12, Folate, B6, and need for Vitamin C.
See full descriptionBlood Chemistry
An iron-containing metalloprotein that transports oxygen from the lungs to the rest of the body. Levels may indicate anaemia from Iron, Copper, B6, Folate, dehydration, poor oxygen deliverability, adrenal dysfunction, blood loss, gastric inflammation, intestinal parasites, malabsorption.
See full descriptionBlood Chemistry
A group of specialised immune cells consisting of B cells, T cells and NK cells that work together to defend the body against pathogens and cancer cells. Levels may indicate acute or chronic viral or bacterial infection, inflammation, toxicity, oxidative stress, anaemia, hypothyroidism, asthma or chronic stress.
See full descriptionBlood Chemistry
A group of specialised immune cells consisting of B cells, T cells and NK cells that work together to defend the body against pathogens and cancer cells. Levels may indicate acute or chronic viral or bacterial infection, inflammation, toxicity, oxidative stress, anaemia, hypothyroidism, asthma or chronic stress.
See full descriptionBlood Chemistry
MCH is a measure of the average weight of haemoglobin per red blood cell. Levels may indicate hypochlorhydria, heavy metals, blood loss, anaemia, nutrient deficiencies or alcohol consumption, need for B12, Folate, B6, Iron, Vitamin C.
See full descriptionBlood Chemistry
MCHC is a measure of the average concentration of haemoglobin in red blood cells. Levels may indicate hypochlorhydria, heavy metals, blood loss, anaemia, nutrient deficiencies or alcohol consumption. Need for B12, Folate, B6, Iron.
See full descriptionBlood Chemistry
Mean Corpuscular Volume is an estimate of the average size (volume) of red blood cells. Levels may indicate hypochlorhydria, heavy metals, blood loss, anaemia, nutrient deficiencies or alcohol consumption. Need for B12, Folate, B6, Iron, Vitamin C.
See full descriptionBlood Chemistry
Phagocytic cells that are part of the body’s second line of defense against infection. These are the precursor to macrophages. These specialised cells travel to the site of infection to destroy cancer cells, pathogens and remove dead cells or damaged tissue. Levels may indicate the late stages of an infection, intestinal parasites, liver dysfunction or BPH.
See full descriptionBlood Chemistry
Phagocytic cells that are part of the body’s second line of defense against infection. These are the precursor to macrophages. These specialised cells travel to the site of infection to destroy cancer cells, pathogens and remove dead cells or damaged tissue. Levels may indicate the late stages of an infection, intestinal parasites, liver dysfunction or BPH.
See full descriptionBlood Chemistry
A measure of the average size of platelets in the blood. Levels may indicate increased platelet production, vascular disease, certain cancers, type 2 diabetes, Hashimoto's thyroiditis, aplastic anaemia or cytotoxic drug therapy.
See full descriptionBlood Chemistry
Used to identify viral and bacterial infection. Also used to identify inflammatory processes and metabolic dysfunctions occurring in the body.
See full descriptionBlood Chemistry
The most abundant white blood cell in the body responsible for neutralising pathogens via phagocytosis and unlike other granulocytes, can travel through tight junctions that line blood vessel walls to enter tissues. Levels may indicate acute or chronic viral or bacterial infections, intestinal parasites, chronic stress or inflammation.
See full descriptionBlood Chemistry
The most abundant white blood cell in the body responsible for neutralising pathogens via phagocytosis and unlike other granulocytes, can travel through tight junctions that line blood vessel walls to enter tissues. Levels may indicate acute or chronic viral or bacterial infections, intestinal parasites, chronic stress or inflammation.
See full descriptionBlood Chemistry
Small, anucleated cell fragments involved in clotting, vascular integrity and vasoconstriction. Levels may indicate atherosclerosis, oxidative stress, inflammation, heavy metals, infection, several types of anaemia, blood loss or certain cancers.
See full descriptionBlood Chemistry
A measure of the amount of RBC’s within the blood. RBC’s carry oxygen from the lungs to bodily tissues and transfer carbon dioxide from the tissues to the lungs. Levels may indicate nutrient deficiencies including Vitamins C, B12 and folate, anaemia ie B12, iron, Folate, Copper, dehydration and stress.
See full descriptionBlood Chemistry
Red Blood Cell Distribution Width (RDW) is a measure of the amount of variation in the size of red blood cells. Levels may indicate malabsorption, nutrient deficiencies including Iron, B12 and folate, anaemia, intestinal bleeding, inflammation.
See full descriptionBlood Chemistry
A measure of total white blood cells in the blood. White blood cells are specialised cells of the immune system that fight infection and defend against pathogens such as viruses, bacteria and parasites. They also produce antibodies and memory cells to create immunity against future infection. Levels can indicate chronic viral or bacterial infection. Pancreatic insufficiency, stress.
See full descriptionInflammation
The rate of sedimentation of red blood cells in anti-coagulated blood in one hour. Levels may indicate tissue destruction, inflammation, and may indicate in certain cases presence of pathogens.
See full descriptionSugars
The main energy source of the body. Controlled by hormones including Insulin and Glucagon. Poorly controlled levels are associated with Diabetes, insulin resistance. Inflammatory processes including Metabolic Syndrome and Hypoglycaemia.
See full descriptionThyroid
The portion of triiodothyronine (T3) that is not bound and represents approximately 10% of circulating T3 in the blood. T3 is converted from T4 and the majority occurs in the liver and kidneys. The conversion process is dependent on Selenium and bile levels. Levels can be used to assess Hypo and hyper thyroid status, T4 to T4 conversion efficacy, Selenium sufficiency, and Iodine sufficiency.
See full descriptionThyroid
Less than 0.05% of Total Thyroxine (T4) is free or unbound. The hormone is made in the thyroid gland and is the precursor to T3. Production of T4 is dependent on levels of iodine, co factors like B6, Biopterin, Copper, Zinc, Vitamins B2, B3 and A. Considered by mainstream when combined with TSH to be the gold standard for assessing thyroid function., Levels are assessed to identify thyroid status (hypo and hyper), Iodine sufficiency as well as protein status and liver function.
See full descriptionThyroid
Used to assess thyroid hormone conversion, stress, elevated cortisol.
See full descriptionThyroid
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
See full descriptionThyroid
Also known as T3 resin uptake. Measures the number of unbound sites on the thyroid binding proteins. Levels are used to identify thyroid states (hypo and hyper) as well as selenium and iodine sufficiency. Can also be used to identify how much binding globulins are available to bind to thyroid hormones.
See full descriptionThyroid
A marker to determine how much active T4 is available ie how well the thyroid is functioning. Used to determine hypo and hyper thyroid status.
See full descriptionThyroid
Also known as TG Abs. Used to determine if there is a thyroid autoimmune dysfunction ie Hashimoto’s (Hypo) or Graves (hyper) where the thyroglobulin in the thyroid is attacked.
See full descriptionThyroid
Aka TBG Made in the liver. TBG is a protein that binds and carries T4 and T3 in the blood. There are also other proteins that carry thyroid hormones ie Albumin and Transthyretin. Especially useful where T4 and T3 don't have accompanying thyroid symptoms as levels can also be related to oestrogen, corticosteroids, and liver function.
See full descriptionThyroid
Also known as TPO. TPO is a thyroid gland produced enzyme that attaches the Iodine molecule to tyrosine to make T4. Levels are used to determine an autoimmune thyroid condition - Hashimoto’s.
See full descriptionThyroid
Represents the total of free and bound T3 in the blood, represents approximately 90% of T3. A small percentage is made directly in the thyroid gland and rest predominantly made in the liver and kidney by the conversion of T4 to T3. Levels are used to determine T4 conversion syndrome, Euthyroid sick syndrome, Selenium and Iodine sufficiency and Hyperthyroidism.
See full descriptionThyroid
Major thyroid hormone secreted by the thyroid gland and subject to appropriate levels of Biopterin, Vitamins B6, B2, A, B3 and C as well as sufficient Copper and Zinc. Total T4 represents over 99.5% of the total thyroid hormone available. Levels can help determine, thyroid status (hypo or hyper), Iodine sufficiency,
See full descriptionThyroid
Thyroid Stimulating Hormone is secreted from the anterior pituitary gland and levels are based on a negative feedback loop to signal to the thyroid gland whether to release more Thyroxine or stop releasing. Conventionally along with free T4 the combination is considered the gold standard for assessing thyroid status. Levels are also affected by heavy metal burdens including Aluminium.
See full descriptionThyroid
Also known as TRAbs. Measure the number of antibodies produced antagonistically against the thyroid stimulating receptor. These receptors signal the thyroid to produce thyroid hormones and autoimmune conditions cause the receptors to malfunction. Levels are used to determine Graves' disease (hyperthyroid 90%) and also can be indicated in Hashimoto's (hypothyroid 10%).
See full description
You will need a main test first
£60.00
A useful vitamin add on panel to assess serum nutrient levels that common deficiencies of can lead to dysfunction within the body.
£72.00
LDH is made up of a number of enzymes that are contained in different body tissues. This test identifies the levels of the different LDH enzymes so tat the site of damage, dysfunction and imbalance can be identified.
£112.00
Comprehensive Male Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more
£112.00
Comprehensive Female Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more.
Fibrinogen and Homocysteine are two essential markers to investigate when concerned about Cardiovascular Disease, cognitive, inflammation, and coagulation risks
A comprehensive blood sugar panel add on to provides a complete review of glycaemic management.
£38.00
£51.00
IGF-1 used to establish Growth Hormone deficiency or excess dues to it stability during the day unlike GH.
An Epstein-Barr virus (EBV) antibodies investigation can indicate a current, recent, or past EBV infection. Including: IgG, IgM and Anti Nuclear Antigen (ANA)
An Helicobacter Pylori Antibodies investigation can indicate recent past or longer term past H. Pylori infection
£95.00
A comprehensive set of specialist lipid markers used in the determination of the risks of CVD, inflammation, immune function.
Intracellular measurements of folate and b12, for assessment of levels and methylation capability and pathways.
Anti Mullerian Hormone investigation useful for understanding ovarian reserve and can be used in assessment of PCOS.
Used to identify the ratio between progesterone and estrogen on day 21 of the female cycle as part of a fertility investigation
£70.00
Additional Metals add on panel, identify deficiencies and toxicities. Used in assessments of thyroid, immune, cognitive, inflammation etc
£40.00
Serum measured unbound testosterone.
£32.00
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 3 to weeks. Levels may indicate blood sugar dysregulation.
£55.00
Affects levels of insulin carbohydrate fat and protein levels. Used in supplemental form to assist CH2O metabolism. Note Cr exists in 2 forms Cr (VI) which is toxic and enters the red blood cells and Cr (III). Plasma test measures total Cr and to ID Cr (VI) it will be necessary to measure RBC Cr levels
£125.00
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production
£75.00
Alkaline phosphatase, is made of isoenzymes, each one relating to the tissues they are found including liver, bone, intestine, and placenta.
£30.00
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia. and the effects of supplementation in the case of B12, B6 and Folate anaemias.
C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C4 is Important for the body’s immune function and response to inflammation originating from the HLA system
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
Measurement of IgG, IgM, IgE Immunoglobulins in investigations of the immune system
£30.00
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases.
£20.00
£30.00
Known as ‘the stress hormone’ this steroid hormone plays an essential role in helping the body respond to stress, and regulates a wide range of body processes, including metabolism and immune response.
£45.00
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function etc.
£49.00
£45.00
Also known as holotranscobalamin also see Vitamin B12. Active B12 accounts for approximately 10 to 20% of total B12 levels. Considered to be a more sensitive marker than serum B12 as it degrades faster serum B12 with a short life span.
£85.00
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
£85.00
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, Testosterone and DHT. DHT is the most potent hormone amongst the androgens because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5 alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to the tissue in which it is produced. It is a more potent hormone than testosterone (approx. 1% circulated feely as unbound), it has a slow dissociation (approx. 5x less than testosterone) and long half-life (2x affinity to the androgen receptors). During development and adult life in men, it promotes prostate growth, activity of the sebaceous glands, male pattern baldness and the development of characteristics that are typically associated with men (body hair, muscle growth, and a deep voice). In women DHT levels are associated with issues including hirsutism, amenorrhea, and increased acne.
£58.00
£30.00
Made in the liver comprising of both LDL and Apolipoprotein A. levels, is used to assess, and associated with hypothyroidism, low sex hormone, inflammation and tissue damage, autoimmunity PCOS and kidney and heart disease.
£15.00
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones Progesterone, Testosterone and the Oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an influence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead to many common conditions in the endocrine, immune, cardiovascular, hormonal, and nervous systems.
£140.00
£24.00
£220.00
Cancer Markers: CA19-9, CA125, CA15-3
£87.00
£55.00
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a red blood cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
£110.00
£25.00
Prolactin is a hormone produced in the pituitary gland, and plays a key role in fertility, reproduction, and the stimulation of breast milk production. It is also involved in regulating the immune system, suppressing the stress response, creating and activating new neurons, and stimulating motherly (maternal) behaviour. Men and non-pregnant women generally have low levels of prolactin. In women, prolactin tests help diagnose the causes of absent or irregular menstruation, spontaneous or abnormal breast milk flow or other unexplained discharges. In men, they can help diagnose erectile dysfunction or loss of sex drive (libido).
Our FDX Thyroid Check panel has been created to look further than the norm (traditional blood analysis) to reveal more about your client’s health picture and to identify areas to focus an effective treatment plan. FunctionalDX uses the world’s most advanced blood interpretation technology considers 13 body systems, 7 accessory systems, 7 macronutrient systems, 14 micro-nutrient deficiencies and 40+ clinical dysfunctions. Test guidelines: Fasting blood draw required in the morning. CLICK FOR KIT INSTRUCTIONS
£575.00
£355.00