Investigate the health of your male client.
Our specially devised panels for Male health are the ultimate tool for the modern healthcare practitioner looking for a comprehensive review of a client’s vitality and health that includes sexual health markers.
To create these panels, we have used the principal biomarkers from our best-selling Signature Inspect test and added important key biomarkers for those looking to include additional endocrine, sex hormone and cardiovascular profiles to their client investigations.
FDX Men Inspect identifies the status of over 85 biomarkers including hormones, homocysteine and fasting insulin plus we have added more comprehensive markers to assess function including thyroid, iron, blood sugar management, enzyme status and cholesterol function.
A zinc dependent enzyme, the major function of Alkaline Phosphatase, is to protect your intestinal tract against bacteria, aid in digestion, breakdown fats and some B vitamins, and promote bone formation. As its name suggests it depends on an alkaline environment and is found in all tissues in the human body, but mostly in bones, kidneys, liver, intestines, and placenta. Levels are used to assess zinc need, liver function, Vitamin C need or biliary obstruction as well as bone turnover.See full description
A byproduct generated from normal muscle metabolism through the action of creatine kinase on creatine the muscle fuel. It is filtered through the kidneys for excretion in the urine. Levels may indicate kidney dysfunction, dehydration, excessive muscle breakdown, increased muscle mass, prostate dysfunction, hyperthyroidism and potential methylation issues.See full description
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones progesterone, testosterone and the oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an inﬂuence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead to many common conditions in the endocrine, immune, cardiovascular, hormonal, and nervous systems.See full description
Synthesised from cholesterol, this steroid hormone is produced in the ovaries of premenopausal women, where it acts as a powerful reproductive hormone and is highest during ovulation and lowest during menstruation. As the main hormone of the three naturally produced oestrogens, it is also produced in the testes of men, but in smaller amounts. In both sexes, oestradiol is made in significantly reduced amounts by the brain, fat tissue, and in the walls of the blood vessels.See full description
A soluble liver produced protein that is broken down to produce fibrin which is necessary for clot formation. Levels may indicate hypercoagulation, inflammation, trauma, infections, cancer, cardiovascular disease or increased risk of stroke and liver function.See full description
The portion of triiodothyronine (T3) that is not bound and represents approximately 10% of circulating T3 in the blood. T3 is converted from T4 and the majority occurs in the liver and kidneys. The conversion process is dependent on Selenium and bile levels. Levels can be used to assess Hypo and hyper thyroid status, T4 to T4 conversion efficacy, Selenium sufficiency, and Iodine sufficiency.See full description
Less than 0.05% of Total Thyroxine (T4) is free or unbound. The hormone is made in the thyroid gland and is the precursor to T3. Production of T4 is dependent on levels of iodine, co factors like B6, Biopterin, Copper, Zinc, Vitamins B2, B3 and A. Considered by mainstream when combined with TSH to be the gold standard for assessing thyroid function., Levels are assessed to identify thyroid status (hypo and hyper), Iodine sufficiency as well as protein status and liver function.See full description
Free testosterone (approximately 2-3%) is the portion of testosterone that is not bound to any proteins in the blood and is “free” to enter the cells and exert biological effects. 33-54% percent is weakly bound to albumin (called BIOAVAILABLE), with the rest bound to SHBG (44-65%).See full description
An amino acid produced through methionine metabolism. This methylation process involves Vitamins B6, B12 and folate as well as zinc and co-factors including magnesium and tri methyl glycine all required in the recycling of methionine to homocysteine and back again. Levels may indicate needs in these nutrients, oxidative stress or metabolic syndrome, risks of Alzheimer’s, CVD risks. Depression, dementia, Parkinson’s, oxidative stress, poor detoxification, IBD.See full description
A fasting insulin test identifies the level of insulin after an 8 to 12 hour fast. Insulin is a pancreatic hormone released to manage the process of glucose being transported into the cells for energy production purposes. Levels are associated with Insulin resistance, Diabetes, Metabolic Syndrome, inflammation, Obesity, lipid management and risks of CVD.See full description
A measure of magnesium in the blood. Mg is a mineral necessary for energy production, muscle contraction, nerve function, maintenance of strong bones, protein and carbohydrate metabolism and over 300 enzymatic processes in the body. It is obtained through the diet and is absorbed in the small intestine and colon. Levels may indicate a deficiency due to malabsorption or digestive disorders.See full description
Phagocytic cells that are part of the body’s second line of defense against infection. These are the precursor to macrophages. These specialised cells travel to the site of infection to destroy cancer cells, pathogens and remove dead cells or damaged tissue. Levels may indicate the late stages of an infection, intestinal parasites, liver dysfunction or BPH.See full description
Progesterone is a steroid hormone released in the ovary. In women, it plays important roles in regulating the menstrual cycle and reproduction, by helping to prepare the body for pregnancy, and maintain the early stages of pregnancy. In men, progesterone is involved in the development of sperm, and is produced at a much lower level than in women. It can help diagnose a failing pregnancy, determine the cause of infertility, or diagnose the cause of abnormal uterine bleeding, as well as adrenal diseases such as congenital adrenal hyperplasia.See full description
Prostate specific antigen (PSA) is a protein that is made in the prostate in two forms - complexed and free. Complexed PSA is bound to other proteins, while free PSA is not bound to anything. Total PSA tests are mainly used to screen for prostate cancer; however, it is not specific enough to diagnose prostate cancer on its own. Free PSA tests can help men with slightly high total PSA levels to help determine whether or not they should get a prostate biopsy. Prostate tumors normally produce complexed PSA, while normal prostate cells produce free PSA. Free PSA tests are used to find the PSA free/total ratio. A high ratio means that you do not need a prostate biopsy.See full description
This protein is produced by the liver, controlled by sex hormones, thyroid hormones, insulin, and dietary factors and binds to sex hormones - testosterone, DHT (dihydrotestosterone), and oestrogen (estradiol). It helps transport them in the blood. SHBG levels, which change with age, vary between men and women, and can help control the levels of androgens and oestrogens in the body. It can help to determine testosterone levels in the blood, since around 40-60% of total testosterone is bound to SHBG in men.See full description
This test measures the amount of both testosterones bound to proteins (sex hormone-binding globulin and albumin) and free (not bound to any proteins) testosterone in the blood. Testosterone is a hormone mainly produced by the testes in men, or ovaries in women. Testosterone’s diverse range of effects on many different organs and tissues includes bone health building and maintaining muscle mass and strength; increasing lean body mass and fat loss; increasing red blood cell production; improving libido and sexual function, increasing sperm production, regulating mood, brain function and memory.See full description
Represents the total of free and bound T3 in the blood, represents approximately 90% of T3. A small percentage is made directly in the thyroid gland and rest predominantly made in the liver and kidney by the conversion of T4 to T3. Levels are used to determine T4 conversion syndrome, Euthyroid sick syndrome, Selenium and Iodine sufficiency and Hyperthyroidism.See full description
Major thyroid hormone secreted by the thyroid gland and subject to appropriate levels of Biopterin, Vitamins B6, B2, A, B3 and C as well as sufficient Copper and Zinc. Total T4 represents over 99.5% of the total thyroid hormone available. Levels can help determine, thyroid status (hypo or hyper), Iodine sufficiency,See full description
Thyroid Stimulating Hormone is secreted from the anterior pituitary gland and levels are based on a negative feedback loop to signal to the thyroid gland whether to release more Thyroxine or stop releasing. Conventionally along with free T4 the combination is considered the gold standard for assessing thyroid status. Levels are also affected by heavy metal burdens including Aluminium.See full description
A measure of the total amount of B12 in the serum. B12 is essential in methylation, important for the nervous system and for red blood cell production. Levels may indicate low dietary intake, malabsorption, Hypochlorhydria, autoimmunity, Anaemia or excessive alcohol intakeSee full description
A measure of the level of 25 (OH) D in the blood. Vitamin D is essential for bone health, brain health and immune function. Levels may indicate a deficiency due to inadequate exposure to sunlight, genetics, insufficient dietary intake, or toxicity due to excessive supplementation; and can be associated with risks of Cancer, Hypertension, chronic pain and inflammation, Diabetes and Depression.See full description
A measure of iron bound to transferrin and serum proteins. It represents 1/3 of the total iron binding capacity of transferrin. 70% of iron is bound to haemoglobin. On its own, it is a relatively poor marker of iron status. Levels may indicate haemochromatosis, haemolytic anaemia, liver damage, hypochlorhydria, Vit B6 deficiency, poor iron intake or absorption, blood loss, chronic disease, pathogen infection, progesterone birth control pills.See full description
You will need a main test first
LDH is made up of a number of enzymes that are contained in different body tissues. This test identifies the levels of the different LDH enzymes so tat the site of damage, dysfunction and imbalance can be identified.
Investigation for identifying autoimmune disease on the TSH receptors usually prevalent in Grave's disease (90%).
IGF-1 used to establish Growth Hormone deficiency or excess dues to it stability during the day unlike GH.
An Epstein-Barr virus (EBV) antibodies investigation can indicate a current, recent, or past EBV infection. Including: IgG, IgM and Anti Nuclear Antigen (ANA)
An Helicobacter Pylori Antibodies investigation can indicate recent past or longer term past H. Pylori infection
Serum measured unbound testosterone.
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 3 to weeks. Levels may indicate blood sugar dysregulation.
Affects levels of insulin carbohydrate fat and protein levels. Used in supplemental form to assist CH2O metabolism. Note Cr exists in 2 forms Cr (VI) which is toxic and enters the red blood cells and Cr (III). Plasma test measures total Cr and to ID Cr (VI) it will be necessary to measure RBC Cr levels
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production
Alkaline phosphatase, is made of isoenzymes, each one relating to the tissues they are found including liver, bone, intestine, and placenta.
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia. and the effects of supplementation in the case of B12, B6 and Folate anaemias.
C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C4 is Important for the body’s immune function and response to inflammation originating from the HLA system
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
Measurement of IgG, IgM, IgE Immunoglobulins in investigations of the immune system
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases.
Known as ‘the stress hormone’ this steroid hormone plays an essential role in helping the body respond to stress, and regulates a wide range of body processes, including metabolism and immune response.
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function etc.
Also known as holotranscobalamin also see Vitamin B12. Active B12 accounts for approximately 10 to 20% of total B12 levels. Considered to be a more sensitive marker than serum B12 as it degrades faster serum B12 with a short life span.
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, Testosterone and DHT. DHT is the most potent hormone amongst the androgens because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5 alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to the tissue in which it is produced. It is a more potent hormone than testosterone (approx. 1% circulated feely as unbound), it has a slow dissociation (approx. 5x less than testosterone) and long half-life (2x affinity to the androgen receptors). During development and adult life in men, it promotes prostate growth, activity of the sebaceous glands, male pattern baldness and the development of characteristics that are typically associated with men (body hair, muscle growth, and a deep voice). In women DHT levels are associated with issues including hirsutism, amenorrhea, and increased acne.
Made in the liver comprising of both LDL and Apolipoprotein A. levels, is used to assess, and associated with hypothyroidism, low sex hormone, inflammation and tissue damage, autoimmunity PCOS and kidney and heart disease.
Cancer Markers: CA19-9, CA125, CA15-3
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a red blood cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
Our FDX Men Inspect panel has been created to look further than the norm (traditional blood analysis) to reveal more about your client’s health picture and to identify areas to focus an effective treatment plan. FunctionalDX uses the world’s most advanced blood interpretation technology considers 13 body systems, 7 accessory systems, 7 macronutrient systems, 14 micro-nutrient deficiencies and 40+ clinical dysfunctions.
Fasting blood draw required in the morning.