Improve performance and stress resilience
With the help of modern technology, our work environments are able to transcend the typical office and expand into what was leisure time.
Work-related stress is growing. It is no secret that stress impacts how we function and our performance – both at work and in your personal life. In 2019, stress, depression, or anxiety accounted for 44% of all work-related ill health cases and 54% of all working days lost due to ill health, contributing to over 12.8 million lost working days in the UK.
Chronic stress causes the poor functioning of the immune system, glycaemic system, impaired performance, and loss of cognitive function. When exogenous work stress is compounded with physiological endogenous stressors, serious dysfunction can occur.
FDX WorkPlace is designed to provide a thorough review of the current health and functioning of the body to reveal the hidden effects of exogenous and endogenous stress upon the body. Using key biomarkers to consider mitochondrial function, sugar and lipid management, chronic inflammation, immune function, oxidative stress, and thyroid hormones along with key nutrient status.
The most abundant metal and in the earth’s crust. Widely used in manufacturing, health and beauty products including antiperspirants, and lipsticks as well as edible cake decorations and more. Exposure is common and excess is detrimental to health and wellbeing and long term exposure and overload to excretory processes can lead to increased levels and elevated risks of toxicity as well as increasing cognitive risks including Alzheimer’s and Dementia as well as associations with anaemia, and bone strength reduction.See full description
Apo A is a constituent of HDL and assists in the binding of cholesterol and fats transport from blood vessels and cells preventing plaque formation. It has a role in cognitive function, in the immune system as an agent against pathogens and detoxifies bacterial toxins. Used as a predictor for CVD and inflammation.See full description
Apolipoprotein B is the backbone of LDL, and is part of the delivery system to deliver cholesterol from the liver. A main contributor to atherosclerosis and heart disease. Linked to immune function and is a measure of CVD risk. Levels are linked with obesity, hypothyroidism, insulin resistance and diabetes. Risk factors also include Alzheimer’s, cognitive function, heart disease and possibly cancer.See full description
A steroid found in all cells and plasma. Cholesterol is an essential lipid that is obtained through diet and produced in the liver. It is essential for life but can be harmful if levels are too high. It helps to form cell membranes and is used in the production of hormones, vitamin D and bile salts. Levels may indicate oxidative stress, inflammation, insulin resistance, blood glucose dysregulation, poor thyroid function, magnesium deficiency, dehydration, liver or kidney dysfunction or familial hypercholesterolemia., heavy metal load, adrenal sufficiency, gallbladder function.See full description
Known as ‘the stress hormone’ this steroid hormone plays an essential role in helping the body respond to stress, and regulates a wide range of body processes, including metabolism and immune response. This test helps identify degrees of stress levels, diagnose adrenal glands dysfunction, and disorders such as underactive, or damaged adrenal glands due to insufficient or excessive cortisol production.See full description
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones progesterone, testosterone and the oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an inﬂuence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead to many common conditions in the endocrine, immune, cardiovascular, hormonal, and nervous systems.See full description
Synthesised from cholesterol, this steroid hormone is produced in the ovaries of premenopausal women, where it acts as a powerful reproductive hormone and is highest during ovulation and lowest during menstruation. As the main hormone of the three naturally produced oestrogens, it is also produced in the testes of men, but in smaller amounts. In both sexes, oestradiol is made in significantly reduced amounts by the brain, fat tissue, and in the walls of the blood vessels.See full description
A measure of the amount of iron stored in the body. The most sensitive test to assess iron deficiency. Levels may indicate haemochromatosis, excess iron intake, inflammation, oxidative stress, liver dysfunction, excessive blood loss or iron deficiency anaemia.See full description
An amino acid produced through methionine metabolism. This methylation process involves Vitamins B6, B12 and folate as well as zinc and co-factors including magnesium and tri methyl glycine all required in the recycling of methionine to homocysteine and back again. Levels may indicate needs in these nutrients, oxidative stress or metabolic syndrome, risks of Alzheimer’s, CVD risks. Depression, dementia, Parkinson’s, oxidative stress, poor detoxification, IBD.See full description
A fasting insulin test identifies the level of insulin after an 8 to 12 hour fast. Insulin is a pancreatic hormone released to manage the process of glucose being transported into the cells for energy production purposes. Levels are associated with Insulin resistance, Diabetes, Metabolic Syndrome, inflammation, Obesity, lipid management and risks of CVD.See full description
LDH (Lactate Dehydrogenase) Measures the level of enzyme. LDH plays a part in energy (carbohydrate) production referring to the reversible lactate to pyruvate pathway. Levels can relate to issues with the 5 main tissues it is found in (see LDH Isoenzymes) and glycemic management,See full description
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function, maintenance of strong bones, carbohydrate and protein metabolism, and over 300 enzymatic processes in the body. It is obtained through diet and is absorbed in the small intestine and colon. Levels may indicate deficiency due to malabsorption or gastrointestinal disorders.See full description
A measure of the total amount of B12 in the serum. B12 is essential in methylation, important for the nervous system and for red blood cell production. Levels may indicate low dietary intake, malabsorption, Hypochlorhydria, autoimmunity, Anaemia or excessive alcohol intakeSee full description
A measure of the level of 25 (OH) D in the blood. Vitamin D is essential for bone health, brain health and immune function. Levels may indicate a deficiency due to inadequate exposure to sunlight, genetics, insufficient dietary intake, or toxicity due to excessive supplementation; and can be associated with risks of Cancer, Hypertension, chronic pain and inflammation, Diabetes and Depression.See full description
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases. Used to assess copper sufficiency, inflammation needs for copper, zinc, anaemia, toxicity, and immune function. Is also used as an Alzheimer’s risk marker, Parkinson’s, Iron status, obesity, and liver damage.See full description
A measure of a type of lipoprotein that transports cholesterol from the liver to various tissues in the body. Elevated levels can cause fatty deposits to accumulate in the arteries increasing the risk for atherosclerosis and cardiovascular disease. Levels are measured to assess risks of the aforementioned as well as metabolic syndrome, oxidative stress and fatty liver.See full description
The portion of triiodothyronine (T3) that is not bound and represents approximately 10% of circulating T3 in the blood. T3 is converted from T4 and the majority occurs in the liver and kidneys. The conversion process is dependent on Selenium and bile levels. Levels can be used to assess Hypo and hyper thyroid status, T4 to T4 conversion efficacy, Selenium sufficiency, and Iodine sufficiency.See full description
Less than 0.05% of Total Thyroxine (T4) is free or unbound. The hormone is made in the thyroid gland and is the precursor to T3. Production of T4 is dependent on levels of iodine, co factors like B6, Biopterin, Copper, Zinc, Vitamins B2, B3 and A. Considered by mainstream when combined with TSH to be the gold standard for assessing thyroid function., Levels are assessed to identify thyroid status (hypo and hyper), Iodine sufficiency as well as protein status and liver function.See full description
Haemoglobin A1C measures the amount of glucose that combines with Haemoglobin (glycosylation) over the life of the red blood cells i.e. approximately 90 days. Levels therefore can identify long term glucose management and control as well as Hypoglycaemia. Unlike a fasting glucose test this marker does require fasting.See full description
A measure of iron bound to transferrin and serum proteins. It represents 1/3 of the total iron binding capacity of transferrin. 70% of iron is bound to haemoglobin. On its own, it is a relatively poor marker of iron status. Levels may indicate haemochromatosis, haemolytic anaemia, liver damage, hypochlorhydria, Vit B6 deficiency, poor iron intake or absorption, blood loss, chronic disease, pathogen infection, progesterone birth control pills.See full description
A digestive enzyme produced by the pancreas that helps the body to digest and absorb fats. Levels may indicate pancreatitis, pancreatic sufficiency, gallbladder dysfunction, kidney disease or peptic ulcers.See full description
Thyroid Stimulating Hormone is secreted from the anterior pituitary gland and levels are based on a negative feedback loop to signal to the thyroid gland whether to release more Thyroxine or stop releasing. Conventionally along with free T4 the combination is considered the gold standard for assessing thyroid status. Levels are also affected by heavy metal burdens including Aluminium.See full description
A type of lipid primarily obtained through diet and from the conversion of excess dietary calories into fat for storage. Levels may indicate excess CHO intake and an increased risk for cardiovascular disease, biliary and liver dysfunction, autoimmune processes, metabolic syndrome, insulin resistance, poor fat processing, hypo and hyper-thryoidism.See full description
A positively charged (cation) electrolyte located primarily in the extracellular fluid necessary for muscle contraction, nutrient absorption, neurological functioning and maintaining pH balance and osmotic pressure. Levels may indicate adrenal dysfunction, kidney dysfunction or dehydration.See full description
A measure of the ratio of sodium to potassium in the blood. Levels may indicate excessive sodium intake, poor diet, hypertension or cardiovascular disease, chronic or acute stress levelsSee full description
Represents the total of free and bound T3 in the blood, represents approximately 90% of T3. A small percentage is made directly in the thyroid gland and rest predominantly made in the liver and kidney by the conversion of T4 to T3. Levels are used to determine T4 conversion syndrome, Euthyroid sick syndrome, Selenium and Iodine sufficiency and Hyperthyroidism.See full description
Major thyroid hormone secreted by the thyroid gland and subject to appropriate levels of Biopterin, Vitamins B6, B2, A, B3 and C as well as sufficient Copper and Zinc. Total T4 represents over 99.5% of the total thyroid hormone available. Levels can help determine, thyroid status (hypo or hyper), Iodine sufficiency,See full description
You will need a main test first
LDH is made up of a number of enzymes that are contained in different body tissues. This test identifies the levels of the different LDH enzymes so tat the site of damage, dysfunction and imbalance can be identified.
Comprehensive Male Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more
Comprehensive Female Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more.
Investigation for identifying autoimmune disease on the TSH receptors usually prevalent in Grave's disease (90%).
IGF-1 used to establish Growth Hormone deficiency or excess dues to it stability during the day unlike GH.
An Epstein-Barr virus (EBV) antibodies investigation can indicate a current, recent, or past EBV infection. Including: IgG, IgM and Anti Nuclear Antigen (ANA)
An Helicobacter Pylori Antibodies investigation can indicate recent past or longer term past H. Pylori infection
Anti Mullerian Hormone investigation useful for understanding ovarian reserve and can be used in assessment of PCOS.
Serum measured unbound testosterone.
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 3 to weeks. Levels may indicate blood sugar dysregulation.
Affects levels of insulin carbohydrate fat and protein levels. Used in supplemental form to assist CH2O metabolism. Note Cr exists in 2 forms Cr (VI) which is toxic and enters the red blood cells and Cr (III). Plasma test measures total Cr and to ID Cr (VI) it will be necessary to measure RBC Cr levels
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production
Alkaline phosphatase, is made of isoenzymes, each one relating to the tissues they are found including liver, bone, intestine, and placenta.
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia. and the effects of supplementation in the case of B12, B6 and Folate anaemias.
C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C4 is Important for the body’s immune function and response to inflammation originating from the HLA system
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
Measurement of IgG, IgM, IgE Immunoglobulins in investigations of the immune system
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases.
Also known as holotranscobalamin also see Vitamin B12. Active B12 accounts for approximately 10 to 20% of total B12 levels. Considered to be a more sensitive marker than serum B12 as it degrades faster serum B12 with a short life span.
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, Testosterone and DHT. DHT is the most potent hormone amongst the androgens because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5 alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to the tissue in which it is produced. It is a more potent hormone than testosterone (approx. 1% circulated feely as unbound), it has a slow dissociation (approx. 5x less than testosterone) and long half-life (2x affinity to the androgen receptors). During development and adult life in men, it promotes prostate growth, activity of the sebaceous glands, male pattern baldness and the development of characteristics that are typically associated with men (body hair, muscle growth, and a deep voice). In women DHT levels are associated with issues including hirsutism, amenorrhea, and increased acne.
Made in the liver comprising of both LDL and Apolipoprotein A. levels, is used to assess, and associated with hypothyroidism, low sex hormone, inflammation and tissue damage, autoimmunity PCOS and kidney and heart disease.
Cancer Markers: CA19-9, CA125, CA15-3
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a red blood cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
FDX WorkPlace assessment considers 13 body systems, 7 accessory systems, 7 macronutrient systems, 14 micro-nutrient deficiencies and 40 clinical dysfunctions to reveal more about your client’s health picture and help them to achieve their optimal performance.
Fasting blood draw required in the morning.