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Blood Chemistry
Basophils %
A type of white blood cell (granulocyte) that alerts the body to infection by secreting immune substances that influence inflammation and coagulation. In tissues they are referred to as mast cells. These specialised immune cells play an important role in inflammation and prevention of clotting in inflamed tissues. Levels may indicate inflammation, intestinal parasites, infection, endocrine dysfunction or hypothyroidism.
See full descriptionBlood Chemistry
Basophils No
A type of white blood cell (granulocyte) that alerts the body to infection by secreting immune substances that influence inflammation and coagulation. In tissues they are referred to as mast cells. These specialised immune cells play an important role in inflammation and prevention of clotting in inflamed tissues. Levels may indicate inflammation, intestinal parasites, infection, endocrine dysfunction, or hypothyroidism.
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Eosinophils %
A type of white blood cell (granulocyte) that secretes important immune substances that influence the inflammatory response. These specialised immune cells are primarily involved in allergic reactions and in host defense against parasitic infection. Levels may indicate intestinal parasites, food/environmental allergies or sensitivities, chronic stress or atopic conditions.
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Eosinophils No
A type of white blood cell (granulocyte) that secretes important immune substances that influence the inflammatory response. These specialised immune cells are primarily involved in allergic reactions and in host defense against parasitic infection. Levels may indicate intestinal parasites, food/environmental allergies or sensitivities, chronic stress or atopic conditions.
See full descriptionBlood Chemistry
Haematocrit
A measure of the percentage of blood volume that consists of red blood cells in a given percentage of centrifuged red blood. Levels may indicate dehydration, malabsorption, asthma, adrenal dysfunction, blood loss, gastric inflammation, thymus hypofunction, liver disease, hypothyroidism, or nutrient deficiencies or anaemia from iron, B12, Folate, B6, and need for Vitamin C.
See full descriptionBlood Chemistry
Haemoglobin
An iron-containing metalloprotein that transports oxygen from the lungs to the rest of the body. Levels may indicate anaemia from Iron, Copper, B6, Folate, dehydration, poor oxygen deliverability, adrenal dysfunction, blood loss, gastric inflammation, intestinal parasites, malabsorption.
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Lymphocytes %
A group of specialised immune cells consisting of B cells, T cells and NK cells that work together to defend the body against pathogens and cancer cells. Levels may indicate acute or chronic viral or bacterial infection, inflammation, toxicity, oxidative stress, anaemia, hypothyroidism, asthma or chronic stress.
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Lymphocytes No
A group of specialised immune cells consisting of B cells, T cells and NK cells that work together to defend the body against pathogens and cancer cells. Levels may indicate acute or chronic viral or bacterial infection, inflammation, toxicity, oxidative stress, anaemia, hypothyroidism, asthma or chronic stress.
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MCH - Mean Corpuscular Haemoglobin
MCH is a measure of the average weight of haemoglobin per red blood cell. Levels may indicate hypochlorhydria, heavy metals, blood loss, anaemia, nutrient deficiencies or alcohol consumption, need for B12, Folate, B6, Iron, Vitamin C.
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MCHC - Mean Corpuscular Haemoglobin Concentration
MCHC is a measure of the average concentration of haemoglobin in red blood cells. Levels may indicate hypochlorhydria, heavy metals, blood loss, anaemia, nutrient deficiencies or alcohol consumption. Need for B12, Folate, B6, Iron.
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MCV - Mean Corpuscular Volume
Mean Corpuscular Volume is an estimate of the average size (volume) of red blood cells. Levels may indicate hypochlorhydria, heavy metals, blood loss, anaemia, nutrient deficiencies or alcohol consumption. Need for B12, Folate, B6, Iron, Vitamin C.
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Monocytes %
Phagocytic cells that are part of the body’s second line of defense against infection. These are the precursor to macrophages. These specialised cells travel to the site of infection to destroy cancer cells, pathogens and remove dead cells or damaged tissue. Levels may indicate the late stages of an infection, intestinal parasites, liver dysfunction or BPH.
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Monocytes No
Phagocytic cells that are part of the body’s second line of defense against infection. These are the precursor to macrophages. These specialised cells travel to the site of infection to destroy cancer cells, pathogens and remove dead cells or damaged tissue. Levels may indicate the late stages of an infection, intestinal parasites, liver dysfunction or BPH.
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MPV (Mean Platelet Volume)
A measure of the average size of platelets in the blood. Levels may indicate increased platelet production, vascular disease, certain cancers, type 2 diabetes, Hashimoto's thyroiditis, aplastic anaemia or cytotoxic drug therapy.
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Neutrophil: Lymphocyte Ratio
Used to identify viral and bacterial infection. Also used to identify inflammatory processes and metabolic dysfunctions occurring in the body.
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Neutrophils %
The most abundant white blood cell in the body responsible for neutralising pathogens via phagocytosis and unlike other granulocytes, can travel through tight junctions that line blood vessel walls to enter tissues. Levels may indicate acute or chronic viral or bacterial infections, intestinal parasites, chronic stress or inflammation.
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Neutrophils No
The most abundant white blood cell in the body responsible for neutralising pathogens via phagocytosis and unlike other granulocytes, can travel through tight junctions that line blood vessel walls to enter tissues. Levels may indicate acute or chronic viral or bacterial infections, intestinal parasites, chronic stress or inflammation.
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Platelets
Small, anucleated cell fragments involved in clotting, vascular integrity and vasoconstriction. Levels may indicate atherosclerosis, oxidative stress, inflammation, heavy metals, infection, several types of anaemia, blood loss or certain cancers.
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RBC's
A measure of the amount of RBC’s within the blood. RBC’s carry oxygen from the lungs to bodily tissues and transfer carbon dioxide from the tissues to the lungs. Levels may indicate nutrient deficiencies including Vitamins C, B12 and folate, anaemia ie B12, iron, Folate, Copper, dehydration and stress.
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RDW
Red Blood Cell Distribution Width (RDW) is a measure of the amount of variation in the size of red blood cells. Levels may indicate malabsorption, nutrient deficiencies including Iron, B12 and folate, anaemia, intestinal bleeding, inflammation.
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Reticulocyte count
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia and the effects of supplementation in the case of B12, B6 and Folate anaemias.
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WBC's
A measure of total white blood cells in the blood. White blood cells are specialised cells of the immune system that fight infection and defend against pathogens such as viruses, bacteria and parasites. They also produce antibodies and memory cells to create immunity against future infection. Levels can indicate chronic viral or bacterial infection. Pancreatic insufficiency, stress.
See full descriptionBone Health
Osteocalcin
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production. In the fats cells increases the production of adiponectin which in turn increases the sensitivity to insulin. In muscles cells it promotes energy availability and is involved in exercise capacity. In the...
See full descriptionElectrolytes
Bicarbonate
An estimation of acid-base balance in the blood. Bicarbonate helps to maintain electrical neutrality and plays an important role in transporting CO2 to the lungs and kidneys for excretion. Levels may indicate hypochlorhydria, digestive dysfunction, poor diet, metabolic alkalosis or acidosis, respiratory alkalosis or acidosis or Thiamine deficiency.
See full descriptionElectrolytes
Chloride
A negatively charged (anion) electrolyte located in extracellular fluid that is needed for stomach acid production, maintaining electrical neutrality and pH balance. Along with sodium, chloride helps to regulate normal levels of water in the body. Levels may indicate metabolic acidosis or alkalosis, adrenal hyperfunction / stress or hypochlorhydria.
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Potassium
The main cation electrolyte is located primarily in the intra-cellular fluid with only a small amount found in the plasma, though the relationship is proportionate. Potassium is involved in muscle contraction, nerve conduction, osmotic pressure, pH balance and cellular transport via the sodium-potassium pump. Levels may indicate cellular damage, adrenal dysfunction, tissue destruction acid base balance, insulin dysregulation, dehydration, kidney dysfunction or dehydration.
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Sodium
A positively charged (cation) electrolyte located primarily in the extracellular fluid necessary for muscle contraction, nutrient absorption, neurological functioning and maintaining pH balance and osmotic pressure. Levels may indicate adrenal dysfunction, kidney dysfunction or dehydration.
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Sodium Potassium Ratio
A measure of the ratio of sodium to potassium in the blood. Levels may indicate excessive sodium intake, poor diet, hypertension or cardiovascular disease, chronic or acute stress levels
See full descriptionEnzymes
Amylase
A digestive enzyme produced in the salivary glands and the pancreas that helps the body to digest and absorb carbohydrates. Levels may indicate pancreatic insufficiency, digestive dysfunction, pancreatitis.
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Diamine Oxidase
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
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G6PD
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids, via the liver adipose tissue mammary glands and adrenals. Has an important role in erythrocyte functions Levels are used to determine potential haemolytic anaemia. Haemolysis can be set off by certain triggers including pathogens. Via...
See full descriptionEnzymes
Histamine
A chemical produced by the enzymatic action of histadine. It released by mast cells in response to an allergic immune response. Causes smooth vessels to dilate and activates cells that are involved in irritability and pain responses. Has neurotransmitter roles and is involved in Hydrochloric acid secretion. Used in assessing allergic responses and mast cell activation.
See full descriptionEnzymes
Lipase
A digestive enzyme produced by the pancreas that helps the body to digest and absorb fats. Levels may indicate pancreatitis, pancreatic sufficiency, gallbladder dysfunction, kidney disease or peptic ulcers.
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Superoxide Dismutase
An important antioxidant enzyme that catalyses the conversion of the damaging superoxide radical (produced during normal cellular respiration and energy production) into molecular oxygen and hydrogen peroxide. Different isoforms of the enzyme use zinc/copper, iron, manganese and nickel as cofactors. Low levels are linked to increased oxidative stress and the development of inflammatory conditions.
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Adiponectin
Adiponectin is an adipokine protein and hormone which is mainly released from fat cells – although levels are inversely proportional to the amount of body fat. It has anti-inflammatory effects in macrophages, endothelial tissue, epithelial tissue and muscle cells and it consequently has important cardiovascular and pulmonary protective effects. Adiponectin also increases insulin sensitivity. Higher than normal levels of adiponectin are associated with being underweight, anorexia nervosa...
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Anti-Mullerian hormone
Anti-Mullerian Hormone levels are differentiated by sex and age. It is used as a biomarker for fertility assessment. AMH provides a guide to ovarian reserve and can help identify women who may need to consider freezing their eggs or should be trying for conception sooner rather than later. It is also useful as a biomarker in the assessment of PCOS
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Cortisol Serum am
Known as ‘the stress hormone’ this steroid hormone plays an essential role in helping the body respond to stress, and regulates a wide range of body processes, including metabolism and immune response. This test helps identify degrees of stress levels, diagnose adrenal glands dysfunction, and disorders such as underactive, or damaged adrenal glands due to insufficient or excessive cortisol production.
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DHEA-sulphate
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones progesterone, testosterone and the oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an influence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead...
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Dihydrotestosterone (DHT)
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, testosterone and DHT. DHT is the most potent hormone amongst the androgens and because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to tissue...
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E2: Progesterone Ratio
Used to identify the ratio between progesterone and oestrogen on day 21 of the female cycle as part of a fertility investigation.
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Estradiol E2
Synthesised from cholesterol, this steroid hormone is produced in the ovaries of premenopausal women, where it acts as a powerful reproductive hormone and is highest during ovulation and lowest during menstruation. As the main hormone of the three naturally produced oestrogens, it is also produced in the testes of men, but in smaller amounts. In both sexes, oestradiol is made in significantly reduced amounts by the brain, fat tissue, and in the walls of the blood vessels.
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FSH
Controlled by hormones produced in the pituitary gland, hypothalamus, and ovaries or testes. FSH regulates various hormonal functions in men and women, where insufficient levels in either sex can give rise to infertility. It also controls oestrogen secretion, where it rises during the first half of the menstrual cycle, and decreases after ovulation. This test helps to identify irregular menstrual periods, as well as women who are struggling to get pregnant, going through menopause, or have...
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Ghrelin
Ghrelin is a hormone which is principally released from the stomach and acts in the hypothalamus to signal hunger, stimulate appetite, reduce energy expenditure and increase fat storage. Levels are highest before mealtimes and it may also play a role in stimulating gastric motility and acid secretion in preparation for food. In addition, ghrelin acts on the anterior pituitary to stimulate the release of growth hormone and on pancreatic islet cells to reduce insulin release. Low levels are...
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IGF-1
Similar in structure to insulin, insulin-like growth factor-1 plays a prominent role in the regulation of immunity and inflammation, and an essential role in regulating endocrine growth and development. It works together with the growth hormone (GH) and stimulates the liver to produce IGF-1 which reproduces, and regenerates cells and promotes growth and development. Another important function is to strengthen tissues, thereby improving bone density and building muscle, and promoting healing.
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Leptin
Leptin is secreted by adipocytes and has a dual role, acting as both a hormone and pro-inflammatory adipokine. It plays a key role in energy homeostasis (via receptors in the hypothalamus), by suppressing food intake and increasing energy expenditure, and it therefore acts as a negative feedback regulator of adiposity. Although leptin levels are higher in obesity, high levels are often accompanied by leptin resistance in the hypothalamus, resulting in symptoms of low leptin. Low levels...
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LH
Luteinizing hormone - is one of the main hormones that plays a major role in controlling the reproductive system in both men and women. In men, LH signals the testes to produce testosterone, which in turn, stimulates sperm production. In women, LH performs different roles at different stages of the menstrual cycle. Initially to produce the female sex hormone estradiol. Latterly LH stimulates the production of progesterone, which is required to support the early stages of pregnancy, if...
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Parathyroid hormone
Released from the parathyroid glands, this hormone works with the hormone ‘calcitonin’, to help control calcium and phosphorus levels in the blood, and lower calcium levels when they get too high. It plays a crucial role in the breakdown and formation of bone.
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Progesterone
Progesterone is a steroid hormone released in the ovary. In women, it plays important roles in regulating the menstrual cycle and reproduction, by helping to prepare the body for pregnancy, and maintain the early stages of pregnancy. In men, progesterone is involved in the development of sperm, and is produced at a much lower level than in women. It can help diagnose a failing pregnancy, determine the cause of infertility, or diagnose the cause of abnormal uterine bleeding, as well as adrenal...
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Prolactin
Prolactin is a hormone produced in the pituitary gland, and plays a key role in fertility, reproduction, and the stimulation of breast milk production. It is also involved in regulating the immune system, suppressing the stress response, creating and activating new neurons, and stimulating motherly (maternal) behaviour. Men and non-pregnant women generally have low levels of prolactin. In women, prolactin tests help diagnose the causes of absent or irregular menstruation, spontaneous or...
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Sex Hormone Binding Globulin
This protein is produced by the liver, controlled by sex hormones, thyroid hormones, insulin, and dietary factors and binds to sex hormones - testosterone, DHT (dihydrotestosterone), and oestrogen (estradiol). It helps transport them in the blood. SHBG levels, which change with age, vary between men and women, and can help control the levels of androgens and oestrogens in the body. It can help to determine testosterone levels in the blood, since around 40-60% of total testosterone is bound to...
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Testosterone Bioavailable Calc
Bioavailable testosterone levels, which peak in the early morning, represent the amount of free testosterone and the testosterone bound to albumin (but not SHBG). Unlike the over 50% of testosterone bound to SHBG which is strongly attached, testosterone bound to albumin is weakly attached and easily able to detach and become free testosterone. It is called “bioavailable” because it is easily “available” to be used by cells. All three types of testosterone (Total, Bioavailable and Free)...
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Testosterone Free Calc
Free testosterone (approximately 2-3%) is the portion of testosterone that is not bound to any proteins in the blood and is “free” to enter the cells and exert biological effects. 33-54% percent is weakly bound to albumin (called BIOAVAILABLE), with the rest bound to SHBG (44-65%).
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Testosterone Total
This test measures the amount of both testosterones bound to proteins (sex hormone-binding globulin and albumin) and free (not bound to any proteins) testosterone in the blood. Testosterone is a hormone mainly produced by the testes in men, or ovaries in women. Testosterone’s diverse range of effects on many different organs and tissues includes bone health building and maintaining muscle mass and strength; increasing lean body mass and fat loss; increasing red blood cell production; ...
See full descriptionImmunology
CEA Cancer Marker
Carcinoembryonic Antigens are proteins produced by certain types of cancer cells eg bowel, liver, lung, breast, pancreatic, stomach and ovarian. They may also be detected in non-cancerous conditions including liver disease and inflammatory bowel disease (Crohn’s disease and ulcerative colitis).
See full descriptionImmunology
Complement factors C3 & C4
Complement Factor C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C3 Levels are also used to identify low levels of immune function as well as the identification of autoimmune disease like Lupus, chronic inflammation, diabetes, metabolic syndrome, fatty liver, and CVD. Complement Factor C4 is Important for the body’s immune function and response to inflammation originating from the HLA system. The main...
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GAD Ab's
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also, can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
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Gastric Parietal Ab's
High levels of gastric parietal antibodies are associated with autoimmune gastritis and may also precede the development of pernicious anaemia. The antibodies are produced against the parietal enzyme hydrogen potassium ATPase.
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H.Pylori IgG Antibodies
A measure of antibodies (infection fighting cells) to H Pylori bacteria. Levels may indicate exposure to H Pylori infection
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Immunoglobulins
IgG, IgM and IgE are all B cell secreted antibodies measured in this panel. They are part of the gamma portion of the blood protein globulins and determine the different immune responses depending on the antibody. They are produced in response to pathogens and act as a marking or identifying line of defense. IgE binds to allergens and produces response to allergic signals indicating histamine and mast cell degradation and is involved in parasitic infections like helminths. IgM is responsible...
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Interleukin 6
IL-6 is a cytokine that can be used as a marker of immune system activation. Released from macrophages, levels may be raised with inflammation, infection, autoimmune disease, cardiovascular disease, stroke, diabetes and some cancers. High levels may also be seen after recent exercise (see below) As part of the NFkB inflammatory signalling pathway, IL-6 is rapidly and transiently released in response to infection or injury and stimulates the synthesis of acute phase proteins and the...
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Intrinsic Factor Ab's
Antibodies against intrinsic factor cause impairment of the absorption of vitamin B12 from the digestive tract and may ultimately lead to the development of pernicious anaemia.
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Protein Electrophoresis
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins, Alpha 1 responds to acute phase inflammation and includes thyroid binding globulin and alpha 1 antitrypsin. Alpha 2 includes ceruloplasmin and the A2 component increases in acute phases ie. a marker for inflammation. Beta globulins are essentially transport proteins and include SHBG and transferrin. Gamma globulins are predominantly...
See full descriptionInflammation
Alk Phos Isoenzymes
A zinc dependent enzyme, Alkaline phosphatase, is made of isoenzymes, each one relating to the tissues they are found including liver, bone, intestine, and placenta. Through electrophoresis the percentage present of each fraction can be determined. Levels are used to determine cancerous or benign liver conditions, liver bone intestinal conditions with or without an increase in ALP.
See full descriptionInflammation
CRP
A measure of a liver produced protein that increases with inflammation. It may also increase following infection, a heart attack, surgery or trauma. Levels may indicate acute inflammation, and diets with too much fat or high GI carbohydrates.
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D-Dimer
During inflammation, leukocyte mediated damage to blood vessel walls can lead to vasculitis with activation of the coagulation cascade and thrombus formation. Fibrinolysis of the clot's releases D-dimer protein fragments into the bloodstream. D-dimer may therefore be used to track inflammation and blood vessel damage in inflammatory conditions. Raised levels may be associated with recent injury or surgery, vasculitis, pregnancy, heart disease or infection.
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ESR
The rate of sedimentation of red blood cells in anti-coagulated blood in one hour. Levels may indicate tissue destruction, inflammation, and may indicate in certain cases presence of pathogens.
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Fatty Acid Report
A measure of the ratio of fatty acids in the blood. This test and report are a measurement and report on the levels of omega 3, 6, 5, 7 and 9 fatty acids as well as saturated and trans along with ratios and indexes. Levels may indicate deficiencies, needs and excess, assessment for dietary malabsorption, as well as indicating inflammation and cardiovascular disease risk.
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Fibrinogen
A soluble liver produced protein that is broken down to produce fibrin which is necessary for clot formation. Levels may indicate hypercoagulation, inflammation, trauma, infections, cancer, cardiovascular disease or increased risk of stroke and liver function.
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Homocysteine
An amino acid produced through methionine metabolism. This methylation process involves Vitamins B6, B12 and folate as well as zinc and co-factors including magnesium and tri methyl glycine all required in the recycling of methionine to homocysteine and back again. Levels may indicate needs in these nutrients, oxidative stress or metabolic syndrome, risks of Alzheimer’s, CVD risks. Depression, dementia, Parkinson’s, oxidative stress, poor detoxification, IBD.
See full descriptionInflammation
HsCRP
A highly sensitive measure of CRP, a protein in the blood that increases with inflammation.
See full descriptionInflammation
LDH Isoenzymes
Fractions of LDH (Lactate dehydrogenase) are isoenzymes that are expressed in various blood tissues throughout the body - namely the lungs, heart, blood cells, the brain, lungs, kidneys, placenta, pancreas liver, and muscle. Different isoenzymes are released during tissue damage, and assessment of these can help pinpoint the area of tissue destruction
See full descriptionIron
Ferritin
A measure of the amount of iron stored in the body. The most sensitive test to assess iron deficiency. Levels may indicate haemochromatosis, excess iron intake, inflammation, oxidative stress, liver dysfunction, excessive blood loss or iron deficiency anaemia.
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Iron
A measure of iron bound to transferrin and serum proteins. It represents 1/3 of the total iron binding capacity of transferrin. 70% of iron is bound to haemoglobin. On its own, it is a relatively poor marker of iron status. Levels may indicate haemochromatosis, haemolytic anaemia, liver damage, hypochlorhydria, Vit B6 deficiency, poor iron intake or absorption, blood loss, chronic disease, pathogen infection, progesterone birth control pills.
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TIBC
An estimation of the iron-binding capacity of transferrin. Levels may indicate iron deficiency anaemia, internal blood loss, haemochromatosis, protein malnutrition or malabsorption, pregnancy, chronic infection, or liver dysfunction.
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Total Iron Binding Capacity
An estimation of the iron-binding capacity of transferrin. Levels may indicate iron deficiency anaemia, internal blood loss, haemochromatosis, protein malnutrition or malabsorption, pregnancy, chronic infection or liver dysfunction.
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Transferrin
A measure of the protein in the blood that binds to iron and transports it through the body. Levels may indicate iron deficiency anaemia, infection, protein malnutrition or malabsorption. Produced in the liver levels can indicate iron capacity, inflammation as well as liver function.
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Transferrin Saturation %
A measure of how much serum iron is bound to transferrin. Levels may indicate haemochromatosis, nutrient deficiency anaemias, tissue inflammation, protein malnutrition or malabsorption.
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UIBC
A measure of the portion of iron binding sites on transferrin that are not occupied by iron. UIBC is often measured along with iron and total iron-binding capacity (TIBC) to determine various iron disorders. Levels may indicate haemochromatosis, poor iron intake, blood loss or pregnancy, hypochlorhydria, cobalamin deficiency.
See full descriptionKidney Function
Creatinine
A byproduct generated from normal muscle metabolism through the action of creatine kinase on creatine the muscle fuel. It is filtered through the kidneys for excretion in the urine. Levels may indicate kidney dysfunction, dehydration, excessive muscle breakdown, increased muscle mass, prostate dysfunction, hyperthyroidism and potential methylation issues.
See full descriptionKidney Function
eGFR
A calculated estimate of kidney glomerular filtration rate function. Subject to age gender, race and creatinine levels in the blood. Levels may indicate kidney dysfunction.
See full descriptionKidney Function
Urea
A waste product generated in the liver due to the breakdown of dietary protein; it is filtered through the kidneys for excretion in the urine. Levels may indicate dehydration, malabsorption, pancreatic insufficiency, hypochlorhydria, kidney dysfunction, high protein intake, fatty liver, catabolic stress (adrenal), inadequate protein intake or protein malabsorption, liver disease, also consider increased need to excrete ammonia and consider pathogens.
See full descriptionKidney Function
Urea / Creatinine Ratio
A measure of the ratio between BUN and Creatinine levels in the blood and is used to assess renal function.
See full descriptionLipids
Apo B : Apo A1 ratio
Used a coronary biomarker. Levels are used to assess risks and trends to coronary artery disease, atherosclerosis, CVD, myocardial infarction, and stroke.
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Apolipoprotein A1
Apo A is a constituent of HDL and assists in the binding of cholesterol and fats transport from blood vessels and cells preventing plaque formation. It has a role in cognitive function, in the immune system as an agent against pathogens and detoxifies bacterial toxins. Used as a predictor for CVD and inflammation.
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Apolipoprotein B
Apolipoprotein B is the backbone of LDL, and is part of the delivery system to deliver cholesterol from the liver. A main contributor to atherosclerosis and heart disease. Linked to immune function and is a measure of CVD risk. Levels are linked with obesity, hypothyroidism, insulin resistance and diabetes. Risk factors also include Alzheimer’s, cognitive function, heart disease and possibly cancer.
See full descriptionLipids
Cholesterol Total
A steroid found in all cells and plasma. Cholesterol is an essential lipid that is obtained through diet and produced in the liver. It is essential for life but can be harmful if levels are too high. It helps to form cell membranes and is used in the production of hormones, vitamin D and bile salts. Levels may indicate oxidative stress, inflammation, insulin resistance, blood glucose dysregulation, poor thyroid function, magnesium deficiency, dehydration, liver or kidney dysfunction or familial...
See full descriptionLipids
Cholesterol/HDL Ratio
A better marker to assess CVD risk than cholesterol in its own.
See full descriptionLipids
HDL cholesterol
A measure of a type of lipoprotein that transports cholesterol from the bloodstream to the liver to be excreted in bile; HDL transports cholesterol to the adrenals, ovaries and testes where it is converted into steroid hormones. HDL is considered beneficial. Levels may indicate cardiovascular disease., autoimmune processes, metabolic syndrome, fatty liver etc.
See full descriptionLipids
LDL Cholesterol
A measure of a type of lipoprotein that transports cholesterol from the liver to various tissues in the body. Elevated levels can cause fatty deposits to accumulate in the arteries increasing the risk for atherosclerosis and cardiovascular disease. Levels are measured to assess risks of the aforementioned as well as metabolic syndrome, oxidative stress and fatty liver.
See full descriptionLipids
Lipoprotein (a)
Made in the liver comprising of LDL, Apolipoprotein B and apolipoprotein(a). (note not to be confused with Apo A). It is an independent marker and levels are largely dependent on genetic propensity. It is used to assess CVD risk, heart disease and stroke.
See full descriptionLipids
Lp PLA2 (PLAC)
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
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Non-HDL Cholesterol
Used as a CVD risk assessor. This measure the level of cholesterol that is not carried HDL. Levels can indicate an increased CBD risk, oxidative stress , fatty liver, diabetes, metabolic syndrome, poor dietary regimes.
See full descriptionLipids
Triglycerides
A type of lipid primarily obtained through diet and from the conversion of excess dietary calories into fat for storage. Levels may indicate excess CHO intake and an increased risk for cardiovascular disease, biliary and liver dysfunction, autoimmune processes, metabolic syndrome, insulin resistance, poor fat processing, hypo and hyper-thryoidism.
See full descriptionLipids
Triglycerides / HDL ratio
Used in identifying trends to insulin resistance. Type 2 diabetes and risks of CVD.
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VLDL
A measure of a type of lipoprotein VLDL-C that is produced in the liver and carries triglycerides and cholesterol throughout the body. Elevated levels can cause fatty deposits to accumulate in the arteries increasing the risk for atherosclerosis and cardiovascular disease.
See full descriptionLiver & Gallbladder
ALP
A zinc dependent enzyme, the major function of Alkaline Phosphatase, is to protect your intestinal tract against bacteria, aid in digestion, breakdown fats and some B vitamins, and promote bone formation. As its name suggests it depends on an alkaline environment and is found in all tissues in the human body, but mostly in bones, kidneys, liver, intestines, and placenta. Levels are used to assess zinc need, liver function, Vitamin C need or biliary obstruction as well as bone turnover.
See full descriptionLiver & Gallbladder
ALT
An enzyme found primarily in the liver, with small amounts in the heart, muscles, and kidneys. Levels may indicate liver disease, biliary issues, pancreatitis or alcoholism, fatty liver, need for B6.
See full descriptionLiver & Gallbladder
AST
An intracellular enzyme found primarily in the liver and heart and to a lesser extent in skeletal muscle, kidneys and lungs. It is released into the bloodstream due to cellular or tissue damage. Levels may indicate cardiovascular disease, liver disease, alcoholism, hypothyroidism, viral infection with EBV or CMV, muscle injury or acute pancreatitis, need for B6.
See full descriptionLiver & Gallbladder
AST:ALT Ratio
Assess liver function and progression of liver disease. Levels are used to assess Vitamin B6 sufficiency, liver dysfunction, muscle damage biliary obstruction, alcoholic liver disease, also consider hepatitis, insulin resistance, NAFLD.
See full descriptionLiver & Gallbladder
Bilirubin Direct
A measure of bilirubin that has been conjugated ie. made water soluble in the liver so it can be excreted in the bile. Levels may indicate liver dysfunction or biliary tract obstruction.
See full descriptionLiver & Gallbladder
Bilirubin indirect
A measure of the protein (albumin) bound bilirubin that circulates in the blood on its way to the liver, from the breakdown of red blood cells Levels may indicate increased red blood cell destruction. (haemolysis) and Gilbert's Syndrome.
See full descriptionLiver & Gallbladder
Bilirubin Total
A marker comprising the total of direct (conjugated) and indirect bilirubin. Formed from the breakdown of haemoglobin from red blood cells at the spleen and bone marrow. May be elevated due to excess red blood cell destruction, liver dysfunction, oxidative stress bile duct obstruction, Gilbert's Syndrome or zinc deficiency, oxidative stress, heavy metal load.
See full descriptionLiver & Gallbladder
Gamma GT / GGT
An enzyme mainly found in the liver. Some production from kidney, prostate and pancreas, Levels may indicate liver or biliary obstruction, alcohol excessive use, Pancreatitis, pancreatic insufficiency, need for Vitamin B6 and magnesium
See full descriptionLiver & Gallbladder
LDH
LDH (Lactate Dehydrogenase) Measures the level of enzyme. LDH plays a part in energy (carbohydrate) production referring to the reversible lactate to pyruvate pathway. Levels can relate to issues with the 5 main tissues it is found in (see LDH Isoenzymes) and glycemic management,
See full descriptionMetabolic
Anion Gap
Represents the difference between the electrolyte cations (positive) and the anions (negative). Used for identifying needs for vitamin B1 and acid base states, indicates trends to metabolic acidosis and alkalosis.
See full descriptionMetabolic
Creatine Kinase
Groups of enzymes that play a large role in energy production and found in tissues that use lots of energy i.e. heart, skeletal muscle and the brain. Levels are used to assess damage from the heart (MI), skeletal muscle damage and breakdown, brain damage, and muscle atrophy
See full descriptionMetabolic
Uric Acid
Produced as the end product of purine breakdown. It is predominantly excreted via the kidneys Failure to excrete or overproduction can be implicated in kidney stones and gout. Used in assessing risks of gout atherosclerosis, oxidative stress, arthritis, kidney function, intestinal permeability, methylation function, detoxification issues.
See full descriptionMinerals & Metals
Aluminium Serum
The most abundant metal and in the earth’s crust. Widely used in manufacturing, health and beauty products including antiperspirants, and lipsticks as well as edible cake decorations and more. Exposure is common and excess is detrimental to health and wellbeing and long term exposure and overload to excretory processes can lead to increased levels and elevated risks of toxicity as well as increasing cognitive risks including Alzheimer’s and Dementia as well as associations with anaemia,...
See full descriptionMinerals & Metals
Arsenic
Arsenic is a neurotoxic and carcinogenic metal that is inhibitory to enzymes involved in energy production. Environmental exposures may be from volcanic ash, metal smelting, pesticides, contaminated water and foods grown in contaminated water and soil (eg rice). Raised serum levels may reflect a recent exposure.
See full descriptionMinerals & Metals
Calcium
45% of calcium is inactive and bound to albumin, of the rest 45% is free and active. The calcium test measures total calcium. Calcium an alkali earth metal is essential for muscle contraction, oocyte activations, bone and dental health, blood clotting, nerve impulse transmission, heartbeat regulation and intracellular fluid balance. Levels are used to assess calcium sufficiency, parathyroid function, hydrochloric acid, tissue cell damage, thyroid function, vitamin D sufficiency, Osteoporosis,...
See full descriptionMinerals & Metals
Calcium : Albumin ratio
Used to assess Vitamin D sufficiency, protein deficiency or loss, calcium insufficiency.
See full descriptionMinerals & Metals
Calcium : Phosphorous ratio
A determinant in the assessment of metabolic acidosis or alkalosis. Can be used to identify trends to sympathetic or parasympathetic states.
See full descriptionMinerals & Metals
Chromium
Affects levels of insulin carbohydrate fat and protein levels. Used in supplemental form to assist CH2O metabolism. Note Cr exists in 2 forms Cr (VI) which is toxic and enters the red blood cells and Cr (III). Plasma test measures total Cr and to ID Cr (VI) it will be necessary to measure RBC Cr levels
See full descriptionMinerals & Metals
Copper Serum
Used as a marker to identify skin health, mental health, toxicity esp. estrogen and clearance of, heart disease risk, diabetes bone loss and immune function. Used to assess copper sufficiency, inflammation and presence of inflammatory diseases, Levels used to assess needs for copper, zinc, anaemia, immune function, inflammatory conditions, PMS, pathogen infection, adrenal insufficiency.
See full descriptionMinerals & Metals
Lead
Lead is a neurotoxic heavy metal. Environmental exposures are commonly through fossil fuels, cosmetics, lead paint and pipes in old houses (although this is now less common). Raised serum levels may reflect a recent exposure. Lead exposure can cause anaemia, weakness, kidney and brain damage.
See full descriptionMinerals & Metals
Magnesium Red cell
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function, maintenance of strong bones, carbohydrate and protein metabolism, and over 300 enzymatic processes in the body. It is obtained through diet and is absorbed in the small intestine and colon. Levels may indicate deficiency due to malabsorption or gastrointestinal disorders.
See full descriptionMinerals & Metals
Magnesium Serum
A measure of magnesium in the blood. Mg is a mineral necessary for energy production, muscle contraction, nerve function, maintenance of strong bones, protein and carbohydrate metabolism and over 300 enzymatic processes in the body. It is obtained through the diet and is absorbed in the small intestine and colon. Levels may indicate a deficiency due to malabsorption or digestive disorders.
See full descriptionMinerals & Metals
Mercury
Mercury is a neurotoxic heavy metal. Environmental exposures are commonly through dental amalgams, vaccines, occupational exposures or seafood. Raised serum levels may reflect a recent exposure.
See full descriptionMinerals & Metals
Phosphorus
A measure of inorganic phosphate in the blood. Phosphates combine with calcium to form bones and teeth, are required for nerve and muscle function, energy production and maintaining the body’s pH balance. Levels may indicate vit D toxicity or deficiency, hypoparathyroidism, kidney dysfunction. elevated insulin, high CHO intake, diarrhoea, poor protein digestion or malabsorption.
See full descriptionMinerals & Metals
Red Blood Cell Zinc
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at Red Blood Cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
See full descriptionMinerals & Metals
Selenium Serum
An essential micronutrient. As soils become depleted dietary intake has fallen, and the need to assess increases. Essential for thyroid T4 to T3 conversion, protects LDL from oxidation. Levels used to assess immune function, inflammation, heart disease risk and reproduction capacity esp. male fertility, Protective effect against some cancers.
See full descriptionMinerals & Metals
Zinc Serum
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a serum level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
See full descriptionNutrients
Glutathione
An important cellular and mitochondrial antioxidant involved in the quenching of both oxygen and nitrogen free radicals, it also has a role to play in recycling vitamins C and E within the cell. It is involved in the phase II detoxification of heavy metals and POPs and production of prostaglandins and leukotrienes. Composed of three peptides (cysteine, glycine and glutamic acid) de novo synthesis within the cell is primarily limited by the availability of the amino...
See full descriptionProstate
PSA free
Prostate specific antigen (PSA) is a protein that is made in the prostate in two forms - complexed and free. Complexed PSA is bound to other proteins, while free PSA is not bound to anything. Total PSA tests are mainly used to screen for prostate cancer; however, it is not specific enough to diagnose prostate cancer on its own. Free PSA tests can help men with slightly high total PSA levels to help determine whether they should get a prostate biopsy. Prostate tumors normally produce complexed...
See full descriptionProstate
PSA Ratio
The free prostate-specific antigen (PSA) test is used to measure the level of unbound PSA in the blood, which can be helpful to assess prostate dysfunction, inflammation of the prostate or cancer. Elevated levels of PSA free are associated with Benign Prostatic Hypertrophy. Decreased levels of PSA are associated with an increased risk of prostatic inflammation of cancer.
See full descriptionProstate
PSA total
Prostate specific antigen (PSA) is a protein that is made in the prostate in two forms - complexed and free. Complexed PSA is bound to other proteins, while free PSA is not bound to anything. Total PSA tests are mainly used to screen for prostate cancer; however, it is not specific enough to diagnose prostate cancer on its own. Free PSA tests can help men with slightly high total PSA levels to help determine whether or not they should get a prostate biopsy. Prostate tumors normally produce...
See full descriptionProteins
Albumin
The most abundant plasma protein in serum produced by the liver. It contributes to plasma osmotic gradient, transports nutrients, hormones and other substances in the blood and is needed for tissue maintenance and repair. Levels may indicate dehydration, hydrochloric acid insufficiency, oxidative stress, free radical activity, Vitamin C need, infection, inflammation, liver, or kidney disease.
See full descriptionProteins
Albumin/Globulin Ratio
A measure of the ratio of albumin to globulin in the blood. Levels may indicate dehydration, liver or kidney dysfunction, hypothyroidism, adrenal dysfunction, or immune activation, can also be considered in assessing a hyper coagulative state “sticky blood”.
See full descriptionProteins
APTT
The activated partial thromboplastin clotting time measures how long it takes blood to form a clot. Used in conjunction with other clotting tests such as prothrombin, it mainly indicates how well the intrinsic clotting pathway and the common final pathway are working.
See full descriptionProteins
Ceruloplasmin
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases. Used to assess copper sufficiency, inflammation needs for copper, zinc, anaemia, toxicity, and immune function. Is also used as an Alzheimer’s risk marker, Parkinson’s, Iron status, obesity, and liver damage.
See full descriptionProteins
Globulin
A plasma protein with different subtypes produced by the liver and immune system. Some transport nutrients and some, called Immunoglobulins, help to fight infection. Levels may indicate digestive inflammation, immune insufficiency, Gastritis, Cancer, liver damage, heavy metals, chemical toxicity, immune activation including parasites, elevated oestrogen, Haemolytic Anaemia.
See full descriptionProteins
INR
The international normalised ratio is a measure of blood clotting function and is based on prothrombin time. Poor clotting may result in a bleeding disorder such as unexplained heavy menstrual periods in women, bruising easily or frequent heavy nosebleeds. Overzealous clotting may result in increased risk of thrombus formation such as DVT.
See full descriptionProteins
Prothrombin
Prothrombin is a protein produced by the liver. It is an important clotting factor. The test measures blood clotting time and is often used to monitor the effect of blood thinners such as warfarin or to evaluate liver disease. It reflects the extrinsic pathway and the common coagulation pathway. The result is often expressed as the international normalised ratio which expresses the prothrombin time as a ratio against the standard ‘normal’ prothrombin time.
See full descriptionProteins
Total Protein
The sum of total proteins, ie. comprised of albumin and globulin totals in the blood. Levels may indicate dehydration, malnutrition, amino acid need, inflammatory conditions, hypochlorhydria, kidney or liver disease.
See full descriptionSugars
ALT:AST ratio
To assist in the evaluation of trends to insulin resistance and metabolic syndrome. Levels are used to indicate ageing, metabolic health, insulin resistance, NAFLD metabolic syndrome CVD risk and trends.
See full descriptionSugars
C Peptide
A byproduct of proinsulin production by the pancreas. Proinsulin splits into Insulin and C-Peptide. Unlike Insulin which is cleared in a variable manner c-peptide is cleared at a constant rate making it a more dependable measure of Insulin production. Levels indicate how much Insulin is being produced and indicates blood sugar dysregulation including Type 1 and 2 diabetes.
See full descriptionSugars
Estimated Average Glucose
A calculated value based on HbA1C values giving the average glucose reading over the past 60 to 90 days, it very useful to assist in the prediction of values over time
See full descriptionSugars
Fructosamine
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 2 to 3 weeks. Levels may indicate blood sugar dysregulation.
See full descriptionSugars
Glucose
The main energy source of the body. Controlled by hormones including Insulin and Glucagon. Poorly controlled levels are associated with Diabetes, insulin resistance. Inflammatory processes including Metabolic Syndrome and Hypoglycaemia.
See full descriptionSugars
HBA1C
Haemoglobin A1C measures the amount of glucose that combines with Haemoglobin (glycosylation) over the life of the red blood cells i.e. approximately 90 days. Levels therefore can identify long term glucose management and control as well as Hypoglycaemia. Unlike a fasting glucose test this marker does require fasting.
See full descriptionSugars
Insulin (fasting)
A fasting insulin test identifies the level of insulin after an 8 to 12 hour fast. Insulin is a pancreatic hormone released to manage the process of glucose being transported into the cells for energy production purposes. Levels are associated with Insulin resistance, Diabetes, Metabolic Syndrome, inflammation, Obesity, lipid management and risks of CVD.
See full descriptionThyroid
Free t3
The portion of triiodothyronine (T3) that is not bound and represents approximately 10% of circulating T3 in the blood. T3 is converted from T4 and the majority occurs in the liver and kidneys. The conversion process is dependent on Selenium and bile levels. Levels can be used to assess Hypo and hyper thyroid status, T4 to T4 conversion efficacy, Selenium sufficiency, and Iodine sufficiency.
See full descriptionThyroid
Free t4
Less than 0.05% of Total Thyroxine (T4) is free or unbound. The hormone is made in the thyroid gland and is the precursor to T3. Production of T4 is dependent on levels of iodine, co factors like B6, Biopterin, Copper, Zinc, Vitamins B2, B3 and A. Considered by mainstream when combined with TSH to be the gold standard for assessing thyroid function., Levels are assessed to identify thyroid status (hypo and hyper), Iodine sufficiency as well as protein status and liver function.
See full descriptionThyroid
ft3:rT3 ratio
Used to assess thyroid hormone conversion, stress, elevated cortisol.
See full descriptionThyroid
Reverse T3
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
See full descriptionThyroid
rT3 on own
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
See full descriptionThyroid
T3 Uptake
Also known as T3 resin uptake. Measures the number of unbound sites on the thyroid binding proteins. Levels are used to identify thyroid states (hypo and hyper) as well as selenium and iodine sufficiency. Can also be used to identify how much binding globulins are available to bind to thyroid hormones.
See full descriptionThyroid
T7 Free Thyroxine index
A marker to determine how much active T4 is available ie how well the thyroid is functioning. Used to determine hypo and hyper thyroid status.
See full descriptionThyroid
Thyroglobulin Abs
Also known as TG Abs. Used to determine if there is a thyroid autoimmune dysfunction ie Hashimoto’s (Hypo) or Graves (hyper) where the thyroglobulin in the thyroid is attacked.
See full descriptionThyroid
Thyroid Binding Globulin
Aka TBG Made in the liver. TBG is a protein that binds and carries T4 and T3 in the blood. There are also other proteins that carry thyroid hormones ie Albumin and Transthyretin. Especially useful where T4 and T3 don't have accompanying thyroid symptoms as levels can also be related to oestrogen, corticosteroids, and liver function.
See full descriptionThyroid
Thyroid peroxidase antibody
Also known as TPO. TPO is a thyroid gland produced enzyme that attaches the Iodine molecule to tyrosine to make T4. Levels are used to determine an autoimmune thyroid condition - Hashimoto’s.
See full descriptionThyroid
Total T3
Represents the total of free and bound T3 in the blood, represents approximately 90% of T3. A small percentage is made directly in the thyroid gland and rest predominantly made in the liver and kidney by the conversion of T4 to T3. Levels are used to determine T4 conversion syndrome, Euthyroid sick syndrome, Selenium and Iodine sufficiency and Hyperthyroidism.
See full descriptionThyroid
Total T4
Major thyroid hormone secreted by the thyroid gland and subject to appropriate levels of Biopterin, Vitamins B6, B2, A, B3 and C as well as sufficient Copper and Zinc. Total T4 represents over 99.5% of the total thyroid hormone available. Levels can help determine, thyroid status (hypo or hyper), Iodine sufficiency,
See full descriptionThyroid
TSH
Thyroid Stimulating Hormone is secreted from the anterior pituitary gland and levels are based on a negative feedback loop to signal to the thyroid gland whether to release more Thyroxine or stop releasing. Conventionally along with free T4 the combination is considered the gold standard for assessing thyroid status. Levels are also affected by heavy metal burdens including Aluminium.
See full descriptionThyroid
TSH receptor abs
Also known as TRAbs. Measure the number of antibodies produced antagonistically against the thyroid stimulating receptor. These receptors signal the thyroid to produce thyroid hormones and autoimmune conditions cause the receptors to malfunction. Levels are used to determine Graves' disease (hyperthyroid 90%) and also can be indicated in Hashimoto's (hypothyroid 10%).
See full descriptionVitamins
Active B12
Also known as holotranscobalamin also see Vitamin B12. Active B12 accounts for approximately 10 to 20% of total B12 levels. Considered to be a more sensitive marker than serum B12 as it degrades faster than serum B12 with a short life span making it a more sensitive indicator or B12 deficiency.
See full descriptionVitamins
Folate Red Cell
See Folate. Red cell folate is considered to be a measure for intracellular sufficiency.
See full descriptionVitamins
Folate Serum
A measure of the total amount of folate in the serum. Folate is needed to make red and white blood cells in the bone marrow, convert carbohydrates into energy, and produce DNA and RNA. Adequate intake is extremely important during periods of rapid growth such as pregnancy, infancy, and adolescence. Levels may indicate dietary insufficiency, malabsorption or anaemia, methylation status, anaemia. Consider links to biopterin pathways and links to neurotransmitters like dopamine and serotonin etc.
See full descriptionVitamins
Vitamin A
Vitamin A: The test measures serum retinol levels. Vitamin A can be derived through the diet as the preformed retinol and retinyl esters in animal products and also as the precursor beta-carotene in plant foods. A percentage of the population (studies suggest this may be as high as 45%) are however, unable to convert beta-carotene efficiently into vitamin A. Vitamin A is needed for eye health and also stimulates the growth and activity of white blood cells. It is...
See full descriptionVitamins
Vitamin B1
Thiamine is an essential water-soluble vitamin that is involved in carbohydrate metabolism and energy production. It is also plays an important role in the central nervous system through regulation of chloride channels and is needed for synthesis (and possibly release) of acetylcholine. Low levels are associated with alcohol intake, fatigue, weakness, cardiac arrhythmias, confusion, memory loss, neuropathy, depression, weight loss, pain and ataxia among other things. Severe...
See full descriptionVitamins
Vitamin B12
A measure of the total amount of B12 in the serum. B12 is essential in methylation, important for the nervous system and for red blood cell production. Levels may indicate low dietary intake, malabsorption, Hypochlorhydria, autoimmunity, Anaemia or excessive alcohol intake
See full descriptionVitamins
Vitamin B2
Riboflavin’s main significance is around its essential role in the formation of the two coenzymes: flavin mononeucleotide (FMN); and flavin dinucleotide (FAD). These coenzymes are involved in energy production, phase 1 detoxification via cytochrome P450 enzymes, lipid metabolism and antioxidant protection as a consequence of the role of FAD in the recycling of glutathione via glutathione reductase. It is this latter reaction that is utilised during the assay for riboflavin. Low...
See full descriptionVitamins
Vitamin B3
Niacin is a water-soluble vitamin used to form the coenzymes: nicotine adenine dinucleotide (NADH) and its ionized form (NAD+); and nicotine adenine dinucleotide phosphate (NADPH) and its ionized form (NADP+). These cofactors are used in many important redox and non-redox reactions throughout the body including energy production. Severe niacin deficiency causes the condition pellagra. Low levels are associated with fatigue, depression, memory loss, headache, hallucinations and...
See full descriptionVitamins
Vitamin B5
Pantothenic acid is a water-soluble vitamin. It is a precursor for CoenzymeA which is involved in synthesis of steroid hormones, essential fatty acids, acetylcholine and melatonin. Low levels are associated with fatigue, headaches, irritability, sleep disturbance, muscle cramps, burning or numbness in extremities.
See full descriptionVitamins
Vitamin B6
Vitamin B6 is needed as a cofactor in approximately 100 enzyme reactions in the body. Of these, amino transfer and decarboxylation reactions (needed for production of serotonin from tryptophan) are possibly the most prominent. It is needed for gluconeogenesis and also modulates steroid hormone activity through binding to hormone receptors. Low levels are associated with skin rashes, cracked and sore lips, glossitis, mood changes, weak immune system, fatigue, tingling in extremities,...
See full descriptionVitamins
Vitamin B7
Biotin is important for several carboxylation enzymes – including pyruvate carboxylase involved in energy metabolism, and acetyl CoA carboxylase in fatty acid synthesis. Low levels are associated with alopecia, dry brittle nails and hair, scaly dermatitis, nausea, depression, hallucinations, muscle pain and localised paraesthesia. Cradle cap in babies is thought to be caused by low biotin – possibly because of the role biotin plays in fatty acid synthesis.
See full descriptionVitamins
Vitamin C
A measure of Vitamin C (Ascorbic acid) in the serum. Vitamin C is obtained through diet and helps to maintain connective tissue, skin and bones. It is also a powerful antioxidant. Levels may indicate deficiency.
See full descriptionVitamins
Vitamin D3 (25 OH)
A measure of the level of 25 (OH) D in the blood. Vitamin D is essential for bone health, brain health and immune function. Levels may indicate a deficiency due to inadequate exposure to sunlight, genetics, insufficient dietary intake, or toxicity due to excessive supplementation; and can be associated with risks of Cancer, Hypertension, chronic pain and inflammation, Diabetes and Depression.
See full descriptionVitamins
Vitamin E
Vitamin E is a fat-soluble vitamin consisting of 8 different vitamers. Four of the vitamers are tocopherols and 4 are tocotrienols. The principal function of vitamin E is as an antioxidant to prevent peroxidation of unsaturated fatty acids within the cell membrane. It also protects vitamin A and can increase its storage. Once oxidised, vitamin E can itself be regenerated by vitamin C. Low levels are associated with muscle pain and weakness, numbness and tingling, vision...
See full descriptionFDX 75: Active B12
Also known as holotranscobalamin also see Vitamin B12. Active B12 accounts for approximately 10 to 20% of total B12 levels. Considered to be a more sensitive marker than serum B12 as it degrades faster serum B12 with a short life span.
Included Biomarkers
Vitamins
FDX 37: Active B12 & Red Cell Folate
Intracellular measurements of folate and b12, for assessment of levels and methylation capability and pathways.
Included Biomarkers
Vitamins
FDX 112: Adrenocorticotropic hormone (ACTH)
Included Biomarkers
Hormones
FDX 61: ALP Isoenzymes
Alkaline phosphatase, is made of isoenzymes, each one relating to the tissues they are found including liver, bone, intestine, and placenta.
Included Biomarkers
Inflammation
FDX 86: ANA IFA panel with Titer
Included Biomarkers
FDX 38: Anti Mullerian Hormone
Anti Mullerian Hormone investigation useful for understanding ovarian reserve and can be used in assessment of PCOS.
Included Biomarkers
Hormones
FDX 104: B Vitamins 1: B1, B2, B3 & B6
Included Biomarkers
Vitamins
FDX 105: B Vitamins 2: B1, B2, B3, B5, B6 & B7
Included Biomarkers
Vitamins
FDX 09: Blood Sugar Management
A comprehensive blood sugar panel add on to provides a complete review of glycaemic management.
Included Biomarkers
Sugars
FDX 88: Cancer Markers 1
Cancer Markers: CA19-9, CA125, CA15-3
Included Biomarkers
FDX 70: Ceruloplasmin
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases.
Included Biomarkers
Proteins
FDX 57: Chromium
Affects levels of insulin carbohydrate fat and protein levels. Used in supplemental form to assist CH2O metabolism. Note Cr exists in 2 forms Cr (VI) which is toxic and enters the red blood cells and Cr (III). Plasma test measures total Cr and to ID Cr (VI) it will be necessary to measure RBC Cr levels
Included Biomarkers
Minerals & Metals
FDX 63: Complement factors C3 & C4
C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C4 is Important for the body’s immune function and response to inflammation originating from the HLA system
Included Biomarkers
Immunology
FDX 72: Cortisol AM
Known as ‘the stress hormone’ this steroid hormone plays an essential role in helping the body respond to stress, and regulates a wide range of body processes, including metabolism and immune response.
Included Biomarkers
Hormones
FDX 08: CVD Essential Markers
Fibrinogen and Homocysteine are two essential markers to investigate when concerned about Cardiovascular Disease, cognitive, inflammation, and coagulation risks
Included Biomarkers
Inflammation
FDX 100: Cystatin-C
Included Biomarkers
Kidney Function
FDX 39: Day 21 Ovulation investigation
Used to identify the ratio between progesterone and estrogen on day 21 of the female cycle as part of a fertility investigation
Included Biomarkers
Hormones
FDX 83: DHEA-sulphate
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones Progesterone, Testosterone and the Oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an influence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead to many common conditions in the endocrine, immune, cardiovascular, hormonal, and nervous systems.
Included Biomarkers
Hormones
FDX 77: Diamine Oxidase
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
Included Biomarkers
Enzymes
FDX 78: Dihydrotestosterone
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, Testosterone and DHT. DHT is the most potent hormone amongst the androgens because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5 alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to the tissue in which it is produced. It is a more potent hormone than testosterone (approx. 1% circulated feely as unbound), it has a slow dissociation (approx. 5x less than testosterone) and long half-life (2x affinity to the androgen receptors). During development and adult life in men, it promotes prostate growth, activity of the sebaceous glands, male pattern baldness and the development of characteristics that are typically associated with men (body hair, muscle growth, and a deep voice). In women DHT levels are associated with issues including hirsutism, amenorrhea, and increased acne.
Included Biomarkers
Hormones
FDX 20: Epstein-Barr virus (EBV) Antibodies IgG IgM ANA
An Epstein-Barr virus (EBV) antibodies investigation can indicate a current, recent, or past EBV infection. Including: IgG, IgM and Anti Nuclear Antigen (ANA)
Included Biomarkers
Immunology
FDX 07: Female Hormone Profile
Comprehensive Female Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more.
Included Biomarkers
Hormones
FDX 41: Free Testosterone
Serum measured unbound testosterone.
Included Biomarkers
Hormones
FDX 43: Fructosamine
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 3 to weeks. Levels may indicate blood sugar dysregulation.
Included Biomarkers
Sugars
FDX 64: Glucose-6-phosphate dehydrogenase (G6PD)
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids
Included Biomarkers
Enzymes
FDX 66: Glutamic Acid Decarboxylase Autoantibodies
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
Included Biomarkers
Immunology
FDX 113: hCG Human Chorionic Gonadotropin
Included Biomarkers
Hormones
FDX 35: Helicobacter Pylori Antibodies
An Helicobacter Pylori Antibodies investigation can indicate recent past or longer term past H. Pylori infection
Included Biomarkers
Immunology
FDX 17: IGF-1
IGF-1 used to establish Growth Hormone deficiency or excess dues to it stability during the day unlike GH.
Included Biomarkers
Hormones
FDX 69: IgG, IgM, IgE Immunoglobulins
Measurement of IgG, IgM, IgE Immunoglobulins in investigations of the immune system
Included Biomarkers
Immunology
FDX 303: Index Iron
Included Biomarkers
Iron
FDX 304: Index Lipid
Included Biomarkers
Lipids
FDX 305: Index Liver function
Included Biomarkers
Liver & Gallbladder
FDX 306: Index Renal
Included Biomarkers
Kidney Function
Metabolic
FDX 05: LDH Isoenzymes
LDH is made up of a number of enzymes that are contained in different body tissues. This test identifies the levels of the different LDH enzymes so tat the site of damage, dysfunction and imbalance can be identified.
Included Biomarkers
Inflammation
FDX 82: Lipoprotein (a)
Made in the liver comprising of both LDL and Apolipoprotein A. levels, is used to assess, and associated with hypothyroidism, low sex hormone, inflammation and tissue damage, autoimmunity PCOS and kidney and heart disease.
Included Biomarkers
Lipids
FDX 36: Lipoprotein panels
A comprehensive set of specialist lipid markers used in the determination of the risks of CVD, inflammation, immune function.
Included Biomarkers
Lipids
FDX 67: Lp-PLA2 (PLAC) Cardiovascular investigation
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
Included Biomarkers
Lipids
FDX 06: Male Hormone Profile
Comprehensive Male Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more
Included Biomarkers
Hormones
Prostate
FDX 40: Metals
Additional Metals add on panel, identify deficiencies and toxicities. Used in assessments of thyroid, immune, cognitive, inflammation etc
Included Biomarkers
Minerals & Metals
FDX 107: Nutrient Panel
Nutrient Panel: Vitamins A, C & E, B1, B2, B3, B5, B6, B7, B9, B12, Folate
Included Biomarkers
Vitamins
FDX 111: Oestrogen & Progesterone finger prick test
An additional finger prick test to assess female hormones within the menstrual cycle or days 3/4. This finger prick test is an add on to the Femme Health panels which will be run on day 21.
Included Biomarkers
Hormones
FDX 42-A: Omega 6:3 and Fatty Acids Report add-on
Using a blood spot sample, this test measures 26 fatty acids, which make up about 99% of all the fatty acids in the body. The report provides fatty acid values and structures are analysed in relation to nutrition and its influence on our health. Three values are considered particularly important in nutritional medicine perspective:: Omega-6/3 Ratio Omega-3 Index trans Fat Level This test and report are a measurement and report on the levels of omega 3, 6, 5, 7 and 9 fatty acids as well as saturated and trans along with ratios and indexes. Levels may indicate deficiencies, needs and excess, assessment for dietary malabsorption, as well as indicating inflammation and cardiovascular disease risk. Blood spot test.
Included Biomarkers
Inflammation
FDX 60: Osteocalcin
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production
Included Biomarkers
Bone Health
FDX 80: Parathyroid Hormone
Released from the parathyroid glands, this hormone works with the hormone ‘calcitonin’, to help control calcium and phosphorus levels in the blood, and lower calcium levels when they get too high. It plays a crucial role in the breakdown and formation of bone.
Included Biomarkers
Hormones
FDX 91: Pernicious Anaemia Panel
Included Biomarkers
Immunology
FDX 85: Pregnenolone
Included Biomarkers
FDX 92: Prolactin
Prolactin is a hormone produced in the pituitary gland, and plays a key role in fertility, reproduction, and the stimulation of breast milk production. It is also involved in regulating the immune system, suppressing the stress response, creating and activating new neurons, and stimulating motherly (maternal) behaviour. Men and non-pregnant women generally have low levels of prolactin. In women, prolactin tests help diagnose the causes of absent or irregular menstruation, spontaneous or abnormal breast milk flow or other unexplained discharges. In men, they can help diagnose erectile dysfunction or loss of sex drive (libido).
Included Biomarkers
Hormones
FDX 90: Red Blood Cell Zinc
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a red blood cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
Included Biomarkers
Minerals & Metals
FDX 73: Red Cell magnesium
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function etc.
Included Biomarkers
Minerals & Metals
FDX 62: Reticulocyte
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia. and the effects of supplementation in the case of B12, B6 and Folate anaemias.
Included Biomarkers
Blood Chemistry
FDX 68: Reverse T3
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
Included Biomarkers
Thyroid
FDX 12: Reverse T3 & T3 Uptake
For additional thyroid function investigation, to determine causes of impaired T3 levels, selenium and iodine status, hypo and hyper states, inflammation, stress etc..
Included Biomarkers
Thyroid
FDX 65: Serum Protein Electrophoresis (SPE)
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins
Included Biomarkers
Immunology
FDX 11: Thyroid Antibodies Investigation
Used to help identify potential autoimmune issues (Hashimoto's).
Included Biomarkers
Thyroid
Thyroid Antibodies Investigation - Essentials Add On
Used to help to identify potential auto-immune issues (Hashimoto's).
Included Biomarkers
Thyroid
FDX 13: TSH Receptor Antibodies
Investigation for identifying autoimmune disease on the TSH receptors usually prevalent in Grave's disease (90%).
Included Biomarkers
Thyroid
FDX 1005: UK Next Working Day by 1pm
Included Biomarkers
FDX 56: Vitamin C
A measure of Vitamin C (ascorbic acid) in the serum. Vitamin C is obtained through diet and helps to maintain connective tissue, skin and bones. It is also a powerful antioxidant. Levels may indicate deficiency.
Included Biomarkers
Vitamins
FDX 04: Vitamins
A useful vitamin add on panel to assess serum nutrient levels that common deficiencies of can lead to dysfunction within the body.
Included Biomarkers
Vitamins
Select a Test
- None
- Biology of Functions
- Brain Check
- Brain Check Ultra
- Cardio Check
- FDX Check
- FDX Inspect
- FDX Ultra
- Femme Essential
- Femme Essential+
- Femme Fertility
- Femme Inspect
- Femme Reset
- Femme Ultra
- Fertility For Men
- Man Essential
- Man Essential+
- Man Inspect
- Man Reset
- Man Ultra
- Omega 6:3 and Fatty Acids Report
- Thyroid Baseline
- Thyroid Check
- Thyroid Check +
- Thyroid Inspect
- Thyroid Ultra
- Weight Aware
- Workout
- Workplace
Active B12
Active B12 & Red Cell Folate
Adiponectin
Adrenocorticotropic hormone (ACTH)
ALP Isoenzymes
ANA IFA panel with Titer
Anti Mullerian Hormone
B Vitamins 1: B1, B2, B3 & B6
B Vitamins 2: B1, B2, B3, B5, B6 & B7
Blood Sugar Management
Cancer Markers 1
CEA Cancer Marker
Ceruloplasmin
Chromium
Coagulation Panel
Complement factors C3 & C4
Cortisol AM
CV-19 Antibodies
CVD Essential Markers
Cystatin-C
D-Dimer
Day 21 Ovulation investigation
DHEA-sulphate
Diamine Oxidase
Dihydrotestosterone
Epstein-Barr virus (EBV) Antibodies IgG IgM ANA
Female Hormone Profile
Free & Total PSA
Free Testosterone
Fructosamine
FSH & LH
Glucose & HbA1C
Glucose-6-phosphate dehydrogenase (G6PD)
Glutamic Acid Decarboxylase Autoantibodies
Growth Hormone
hCG Human Chorionic Gonadotropin
Heavy Metal Panel
Helicobacter Pylori Antibodies
IGF-1
IgG, IgM, IgE Immunoglobulins
Index B12
Index Iron
Index Lipid
Index Liver function
Index Renal
Index Thyroid
Index Vitamin D
LDH Isoenzymes
Leptin
Lipoprotein (a)
Lipoprotein panels
Lp-PLA2 (PLAC) Cardiovascular investigation
Male Hormone Profile
Mercury
Metals
Nutrient Panel
Oestrogen & Progesterone finger prick test
Omega 6:3 and Fatty Acids Report add-on
Osteocalcin
Parathyroid Hormone
Pernicious Anaemia Panel
Pregnenolone
Prolactin
Red Blood Cell Zinc
Red Cell magnesium
Reticulocyte
Reverse T3
Reverse T3 & T3 Uptake
Serum Protein Electrophoresis (SPE)
Thyroid Antibodies Investigation
Thyroid Antibodies Investigation - Essentials Add On
Thyroid hormones
TSH Receptor Antibodies
UK Next Working Day by 1pm
Vitamin C
Vitamin D
Vitamins
Vitamins (anti-ox) A, C & E
