Next level 74 biomarker general health investigation
FDX 02
Our Signature blood testing and interpretations offer accurate monitoring of your health status serving as a roadmap for your nutrition plan. Armed with the in-depth analysis of the current health condition, you can now make accurate, patient-specific recommendations about nutrition, supplementation, and nutraceutical use.
Our ‘second level up’ – the FDX inspect – is a solid test panel that gives you more insight on the health status of your client. Zooming into inflammatory markers, blood sugar, thyroid, and vitamin status. Providing you with information on three key vitamins; Folate, B12 and Vitamin D, which are important nutrients to look at when suspecting chronic disease.
This panel also ‘inspects’ the status of important minerals in the blood, such as iron, calcium, and potassium to give you a glimpse of your clients’ hormonal status.
Various
Key Biomarker
The hormone Dehydroepiandrosterone (DHEA) is an important precursor to hormones such as the sex hormones progesterone, testosterone and the oestrogens. It is produced predominantly in the adrenal glands and is involved in the Fight or Flight stress response to resume a calm state after perceived danger/stress has passed. As the most abundant circulating steroid in the body, it has an influence on over 150 known repair functions in both the body and brain. Increased or decreased levels may lead to many common conditions in the endocrine, immune, cardiovascular, hormonal, and nervous systems.
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A measure of the total amount of folate in the serum. Folate is needed to make red and white blood cells in the bone marrow, convert carbohydrates into energy, and produce DNA and RNA. Adequate intake is extremely important during periods of rapid growth such as pregnancy, infancy, and adolescence. Levels may indicate dietary insufficiency, malabsorption or anaemia, methylation status, anaemia. Consider links to biopterin pathways and links to neurotransmitters like dopamine and serotonin etc.
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The portion of triiodothyronine (T3) that is not bound and represents approximately 10% of circulating T3 in the blood. T3 is converted from T4 and the majority occurs in the liver and kidneys. The conversion process is dependent on Selenium and bile levels. Levels can be used to assess Hypo and hyper thyroid status, T4 to T4 conversion efficacy, Selenium sufficiency, and Iodine sufficiency.
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An amino acid produced through methionine metabolism. This methylation process involves Vitamins B6, B12 and folate as well as zinc and co-factors including magnesium and tri methyl glycine all required in the recycling of methionine to homocysteine and back again. Levels may indicate needs in these nutrients, oxidative stress or metabolic syndrome, risks of Alzheimer’s, CVD risks. Depression, dementia, Parkinson’s, oxidative stress, poor detoxification, IBD.
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A fasting insulin test identifies the level of insulin after an 8 to 12 hour fast. Insulin is a pancreatic hormone released to manage the process of glucose being transported into the cells for energy production purposes. Levels are associated with Insulin resistance, Diabetes, Metabolic Syndrome, inflammation, Obesity, lipid management and risks of CVD.
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Represents the total of free and bound T3 in the blood, represents approximately 90% of T3. A small percentage is made directly in the thyroid gland and rest predominantly made in the liver and kidney by the conversion of T4 to T3. Levels are used to determine T4 conversion syndrome, Euthyroid sick syndrome, Selenium and Iodine sufficiency and Hyperthyroidism.
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Major thyroid hormone secreted by the thyroid gland and subject to appropriate levels of Biopterin, Vitamins B6, B2, A, B3 and C as well as sufficient Copper and Zinc. Total T4 represents over 99.5% of the total thyroid hormone available. Levels can help determine, thyroid status (hypo or hyper), Iodine sufficiency,
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A measure of the total amount of B12 in the serum. B12 is essential in methylation, important for the nervous system and for red blood cell production. Levels may indicate low dietary intake, malabsorption, Hypochlorhydria, autoimmunity, Anaemia or excessive alcohol intake
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A measure of the level of 25 (OH) D in the blood. Vitamin D is essential for bone health, brain health and immune function. Levels may indicate a deficiency due to inadequate exposure to sunlight, genetics, insufficient dietary intake, or toxicity due to excessive supplementation; and can be associated with risks of Cancer, Hypertension, chronic pain and inflammation, Diabetes and Depression.
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You will need a main test first
£72.00
LDH is made up of a number of enzymes that are contained in different body tissues. This test identifies the levels of the different LDH enzymes so tat the site of damage, dysfunction and imbalance can be identified.
£112.00
Comprehensive Male Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more
£112.00
Comprehensive Female Hormone panel to provide insight on hormone balance within the body. Hormone levels can impact on energy, sex drive, performance, sleep, concentration and much more.
Fibrinogen and Homocysteine are two essential markers to investigate when concerned about Cardiovascular Disease, cognitive, inflammation, and coagulation risks
A comprehensive blood sugar panel add on to provides a complete review of glycaemic management.
£33.00
Used to help identify potential autoimmune issues (Hashimoto's).
For additional thyroid function investigation, to determine causes of impaired T3 levels, selenium and iodine status, hypo and hyper states, inflammation, stress etc..
Investigation for identifying autoimmune disease on the TSH receptors usually prevalent in Grave's disease (90%).
£38.00
£51.00
IGF-1 used to establish Growth Hormone deficiency or excess dues to it stability during the day unlike GH.
An Epstein-Barr virus (EBV) antibodies investigation can indicate a current, recent, or past EBV infection. Including: IgG, IgM and Anti Nuclear Antigen (ANA)
An Helicobacter Pylori Antibodies investigation can indicate recent past or longer term past H. Pylori infection
£95.00
A comprehensive set of specialist lipid markers used in the determination of the risks of CVD, inflammation, immune function.
Intracellular measurements of folate and b12, for assessment of levels and methylation capability and pathways.
Anti Mullerian Hormone investigation useful for understanding ovarian reserve and can be used in assessment of PCOS.
Used to identify the ratio between progesterone and estrogen on day 21 of the female cycle as part of a fertility investigation
£70.00
Additional Metals add on panel, identify deficiencies and toxicities. Used in assessments of thyroid, immune, cognitive, inflammation etc
£40.00
Serum measured unbound testosterone.
£32.00
A measure of glycated protein formed between glucose and albumin and is a marker for glucose control over the past 3 to weeks. Levels may indicate blood sugar dysregulation.
£55.00
Affects levels of insulin carbohydrate fat and protein levels. Used in supplemental form to assist CH2O metabolism. Note Cr exists in 2 forms Cr (VI) which is toxic and enters the red blood cells and Cr (III). Plasma test measures total Cr and to ID Cr (VI) it will be necessary to measure RBC Cr levels
£125.00
Protein hormone produced in the bone cells (osteoblasts). Binds calcium and is involved in bone regeneration and formation. Once released into the blood can act like a hormone and has direct effects i.e. it affects the beta cells of the pancreas and in turn can increase insulin production
£75.00
Alkaline phosphatase, is made of isoenzymes, each one relating to the tissues they are found including liver, bone, intestine, and placenta.
£30.00
Reticulocytes are newly formed and immature red blood cells that are produced in the bone marrow. They are reported as a percentage of total Red Blood Cells and can be used as an indicator or an individual's ability to produce RBCs. Levels are used to assess the bone marrow’s response to anaemia. and the effects of supplementation in the case of B12, B6 and Folate anaemias.
C3 is Important for the body’s immune function and response to inflammation. The main function is to destroy bacteria and viruses. C4 is Important for the body’s immune function and response to inflammation originating from the HLA system
Glucose 6 Phosphate Dehydrogenase. An enzyme that catalyses the energy (glucose to pyruvate) producing pathway that supplies reducing energy by maintaining the level of NADPH by reducing NADP to NADPH and compound essential in the biosynthesis of fatty acids
Examines the levels of specific blood proteins the Globulins. These are divided into Albumin as well as Alpha 1, Alpha 2, Beta, and Gamma globulins
Type 1 diabetes investigation or latent autoimmune adult diabetes. GAD enzyme is required for the healthy function of the pancreas. The presence of Glutamic Acid Decarboxylase Autoantibodies indicates Type 1 diabetes. Can be used to assess if gestational diabetes is type 1. Also can indicate neurological disorders. Consider in relation to gluten sensitivity and coeliac disease
Measures the amount of lipoprotein associated phospholipase in the blood. Primarily associated with LDL which carried the Lp-PLA2 to the coronary artery walls activating an immune response making plaque. Levels are associated with increased risk of heart attack and stroke and is an excellent coronary marker
£70.00
Considered to be the metabolic brake to counteract the effects of the metabolic accelerator that is T3. Levels are used to identify possible diabetes, effects of fasting, heavy metals, inflammatory, pathogen effects, inflammatory cytokines like IL6 and TN-Alpha, also an indicator of stress.
Measurement of IgG, IgM, IgE Immunoglobulins in investigations of the immune system
£30.00
Copper transport protein binds 95% of circulating copper. Interacts with 120 other proteins. Is an acute phase protein and responds to inflammation and inflammatory diseases.
£20.00
£30.00
Known as ‘the stress hormone’ this steroid hormone plays an essential role in helping the body respond to stress, and regulates a wide range of body processes, including metabolism and immune response.
£45.00
A more accurate measure of magnesium can be obtained via red blood cells which contain 2 – 3x more Mg than serum. Mg is a mineral necessary for energy production, muscle contraction, nerve function etc.
£49.00
£45.00
Also known as holotranscobalamin also see Vitamin B12. Active B12 accounts for approximately 10 to 20% of total B12 levels. Considered to be a more sensitive marker than serum B12 as it degrades faster serum B12 with a short life span.
£85.00
Also known as DAO. Used in the assessment of histamine intolerance which can be caused by the deficiency of DAO or an imbalance between histamine and DAO.
£85.00
Dihydrotestosterone (DHT) is a male sex hormone (androgen). Androgens are endogenous steroid hormones consisting of DHEA, Androstenedione, Testosterone and DHT. DHT is the most potent hormone amongst the androgens because it is not converted to estrogen, it is considered to be a pure androgen. It is created from testosterone via the action of the enzyme 5 alpha-reductase and is produced in the prostate gland, adrenal glands, liver, brain, and hair follicles. Its action is related to the tissue in which it is produced. It is a more potent hormone than testosterone (approx. 1% circulated feely as unbound), it has a slow dissociation (approx. 5x less than testosterone) and long half-life (2x affinity to the androgen receptors). During development and adult life in men, it promotes prostate growth, activity of the sebaceous glands, male pattern baldness and the development of characteristics that are typically associated with men (body hair, muscle growth, and a deep voice). In women DHT levels are associated with issues including hirsutism, amenorrhea, and increased acne.
£25.00
Released from the parathyroid glands, this hormone works with the hormone ‘calcitonin’, to help control calcium and phosphorus levels in the blood, and lower calcium levels when they get too high. It plays a crucial role in the breakdown and formation of bone.
£30.00
Made in the liver comprising of both LDL and Apolipoprotein A. levels, is used to assess, and associated with hypothyroidism, low sex hormone, inflammation and tissue damage, autoimmunity PCOS and kidney and heart disease.
£75.00
£220.00
Cancer Markers: CA19-9, CA125, CA15-3
£87.00
£55.00
Zinc is not stored in the body and dietary intake is essential. Zinc is involved in over 300 enzyme functions. Including the metabolism and function of carbohydrates, proteins and fats. As well involved in immune function, skin health and healing and senses of taste and smell amongst many. Levels are used to assess zinc status at a red blood cell level, hydrochloric acid production, male fertility, inflammation, copper status amongst many.
Our signature panel FDX Inspect has been created to look further than the norm (traditional blood analysis) to reveal more about your client’s health picture and to identify areas to focus an effective treatment plan. FunctionalDX uses the world’s most advanced blood interpretation technology considers 13 body systems, 7 accessory systems, 7 macronutrient systems, 14 micro-nutrient deficiencies and 40+ clinical dysfunctions.
Test guidelines:
Fasting blood draw required in the morning.
£175.00